Results 81 to 90 of about 798,697 (287)

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Role of Language in Identity Formation: An Analysis of Influence of Sanskrit on Identity Formation [PDF]

, 2017
The contents of Brahmajnaana, the Buddhism, the Jainism, the Sabdabrahma Siddhanta and Shaddarsanas will be discussed to present the true meaning of individual’s identity and I.
Varanasi, Varanasi Ramabrahmam
core  

Pentateuch–Joshua: a settler-colonial document of a supplanting society [PDF]

, 2014
This article examines the ideology of Pentateuch–Joshua in comparison with recent social scientific scholarship on settler-colonialism and supplanting societies.
Pitkänen, Pekka M A
core   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

Ethnolanguages in the Media Space of the Republic of Mordovia

Финно-угорский мир
Introduction. The transformation of the information space entails changes in the communication practices of the speakers of various ethnic cultures. Internet resources combined with traditional media provide new, previously unknown opportunities for the ...
Iraida A. Pakshina, Elena N. Maskaeva
doaj   +1 more source

How the COVID-19 pandemic impacts social scientific research on sustainability: questions of methodology, ethics and justice: comment on Santana et al. 2021. [PDF]

Sustain Sci, 2022
Otto D, Haase A.
europepmc   +1 more source

The Constitution of Social Practices [PDF]

, 2017
Practices – specific, recurrent types of human action and activity – are perhaps the most fundamental "building blocks" of social reality. This book argues that the detailed empirical study of practices is essential to effective social-scientific ...
McMillan, Kevin
core  

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Realism and Antirealism [PDF]

, 2016
Our best social scientific theories try to tell us something about the social world. But is talk of a “social world” a metaphor that we ought not take too seriously?
Harp, Randall, Khalifa, Kareem
core  

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source