Results 81 to 90 of about 12,028,240 (312)
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Social simulations: improving interdisciplinary understanding of scientific positioning and validity
, 2010 Because of features that appear to be inherent in many social systems, modellers face complicated and subjective choices in positioning the scientific contribution of their research.
Bell, Keith R.W. +5 more
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Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Кардиоваскулярная терапия и профилактика, 2006 Aim. To compare effects of atorvastatin in the doses of 10 and 20 mg/d on lipid profile, C-reactive protein (hsCRP), fibrinogen levels, as well as vascular wall structure and function in patients with coronary heart disease (CHD) and primary ...
A. V. Susekov +7 more
doaj
Challenges of migration for the social pedagogy in Swedish context
, 2016 The key aspects to how the Swedish social insurance system is implemented are a high degree of universalism and the promotion of equality. The aim of this article is to explore certain issues of complexity in recent societal changes, in order to ...
Dychawy Rosner, Irena
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Los Angeles County Social Survey, 1996 (LACSS)
, 1996 The Los Angeles County Social Survey (LACSS) continues the Los Angeles Metropolitan Area Studies (LAMAS) and the Southern California Social Surveys (SCSS).
University of California, Los Angeles. Institute for Social Science Research.
core +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Los Angeles County Social Survey, 1998 (LACSS)
The Los Angeles County Social Survey (LACSS) continues the Los Angeles Metropolitan Area Studies (LAMAS) and the Southern California Social Surveys (SCSS).
University of California, Los Angeles. Institute for Social Science Research.
core +2 more sources
Social Decision-Making under Scientific Controversy, Expertise, and the Precautionary Principle [PDF]
Integrating scientific inputs into the regulatory process is generally attributed to experts. But, environmental issues are often characterised by an all-pervasive uncertainty and scientific and social controversies which make the experts' task difficult.
Olivier Godard
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