Results 91 to 100 of about 623,753 (303)
Rational Choice, Scientific Method and Social Scientism [PDF]
The eighteenth-century introduction of the scientific method of the natural sciences to the study of social phenomena draws a line between moral philosophy Ethat aspect of ancient and medieval philosophy that dealt with social issues Eand the social ...
Bongo Adi +2 more
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Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Mission, identity and ethics in Mark: Jesus, the patron for outsiders
HTS Teologiese Studies/Theological Studies, 2013 In this contribution the relationship between mission, identity and ethics in Mark was investigated by means of a postcolonial and social-scientific reading, with a focus on patronage as a practice that constituted the main bond of human society in the ...
Ernest van Eck
doaj
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Fafnir, 2023 This article examines the presence and potential applications of care, empathy, and anti-binary approaches in relation to scientific thought and practice in Naomi Mitchison’s first science fiction novel, Memoirs of a Spacewoman (1962).
Grace Borland Sinclair
doaj
Scientific Collaboration Network in Arabic Literary Criticism Articles: A Structural, Clustering, and Author Interaction Analysis [PDF]
نقد ادب معاصر عربیIntroduction: In recent decades, scientific collaborations and research networks have become fundamental pillars of academic progress and development.
Fatemeh Alinezhad Chamazkoti +4 more
doaj +1 more source
Quantitative Economic Modeling vs Methodological Individualism ? [PDF]
During a long time, the Austrian Economic School was against any mathematical formalization in social and economic sciences because it would be opposed to an individualist point of view of social phenomenons.
Buda, Rodolphe
core +1 more source
Bipolarity and Ambivalence in Landscape Architecture [PDF]
, 2010 Our discipline of landscape architecture contains bipolarity, not only in terms of landscape and architecture but also because the idea of landscape is both aesthetic and scientific.
Koh, J.
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Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
, 1958 Criticism of the methods and conclusions of the Enlightenment was initiated almost as soon as the movement itself had begun. It is for this reason that this chapter follows immediately after the one on the Enlightenment, rather than after the later ...
Bloom, Robert L. +6 more
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