Results 101 to 110 of about 141,885 (309)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Behavioral Finance [PDF]

open access: yes
Behavioral finance as a subdiscipline of behavioral economics is finance incorporating findings from psychology and sociology into its theories. Behavioral finance models are usually developed to explain investor behavior or market anomalies when ...
Glaser, Markus   +2 more
core  

Análise comportamental do direito: fundamentos para uma abordagem do direito como ciência comportamental aplicada [PDF]

open access: yes, 2006
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências Jurídicas. Programa de Pós-Graduação em Direito.Este trabalho expõe os fundamentos de uma nova abordagem do direito denominada análise comportamental do direito.
Aguiar, Julio Cesar de
core  

Does deliberate practice surpass didactic training in learning empathy skills? – A randomized controlled study

open access: yesNordic Psychology
A large body of research identifies therapist expressed empathy as one of the most important predictors of psychotherapy outcome. Deliberate practice (DP) is an effective method to improve skills in many fields. We asked if DP also can be used to enhance
Johannes Larsson   +7 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Morality and Prosocial Behavior: the Role of Awareness, Responsibility and Norms in the Norm Activation Model [PDF]

open access: yes, 2009
This paper examines the relationships between variables included in the Norm Activation Model of prosocial behaviour (NAM). Specifically, we evaluate the strength of two commonly used interpretations of this model, namely the NAM as a mediator model and ...
Judith I M De Groot   +5 more
core   +1 more source

Behavioral and neural responses to social rejection: Individual differences in developmental trajectories across childhood and adolescence

open access: yesDevelopmental Cognitive Neuroscience
Dealing with social rejection is challenging, especially during childhood when behavioral and neural responses to social rejection are still developing.
Jeroen D. Mulder   +2 more
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Darwin in mind : new opportunities for evolutionary psychology

open access: yes, 2011
Evolutionary Psychology (EP) views the human mind as organized into many modules, each underpinned by psychological adaptations designed to solve problems faced by our Pleistocene ancestors.
Bolhuis Johan J.   +15 more
core   +1 more source

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