Results 161 to 170 of about 885,530 (314)

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Relationship among temporary separation, attachment styles, and adjustment in first-grade Iranian children

Psychology Research and Behavior Management, 2016
Siyamak Tahmasebi,1 Saman Mafakheri Bashmaq,2 Mansoureh Karimzadeh,3 Robab Teymouri,4 Mahdi Amini,5 Maryam Sadat M vaghefi,6 M Ali Mazaheri7 1Department of Preschool Education, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran ...
Tahmasebi S, Mafakheri Bashmaq S, Karimzadeh M, Teymouri R, Amini M, vaghefi MSM, Mazaheri MA   +6 more
doaj  

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Social cognitive impacts of digital art in metaverse environments: A cross-sectional study of user perception and behavioral patterns. [PDF]

PLoS One
Yang L.
europepmc   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Adaptability factors and behavioral biases of investors in frontier markets: An adaptive market hypothesis perspective. [PDF]

PLoS One
Jannatunnesa J, Mahdzan NS, Md Noman AH.
europepmc   +1 more source

Psychological Science Accelerator Funding and Finance Committee Bylaws Director Assistant Professor of Communication & Social Behavior Visiting Researcher Assistant Professor Research Scientist Postdoctoral Research Fellow Associate Professor Researcher Research Associate

The Funding and Finance Committee serves as an advisory board for the PSA’s Director and Associate Directors on all matters related to finance and funding. The Funding and Finance Committee will work with the PSA’s Director and Associate Directors (hereafter “the PSA Board”) to propose and manage the PSA’s annual operating budget, provide guidance to ...
Hans IJzerman, Neil Lewis, Jr., Flavio Azevedo, Nicholas A. Coles, Nadia Saraí Corral-Frías, Gustav Nilsonne, Lili Lazarevic, Kathleen Schmidt   +7 more
openaire   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source