Results 111 to 120 of about 1,992,889 (305)
Screening for lung cancer: A systematic review of overdiagnosis and its implications
Molecular Oncology, EarlyView.Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz +12 more
wiley +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
The effect of place of living on social acceptance of shared PV projects in Switzerland
Environmental Research: EnergyIn Switzerland, solar power has the greatest potential to further advance the energy transition. As conventional rooftop PV excludes a large share of citizens from personally contributing to climate change mitigation, shared PV (photovoltaics) projects ...
Sophie Ruprecht
doaj +1 more source
Frontiers in PsychologyIntroduction/BackgroundThis study investigates how social exclusion experiences influence antisocial risk-taking behaviors in adolescents by examining the interplay between classroom social acceptance and experimentally induced social exclusion ...
Corinna Lorenz +4 more
doaj +1 more source
Alternatives to Liberal Constitutional Democracy [PDF]
, 2017 The global appeal of liberal constitutional democracy—defined as a competitive multiparty system combined with governance within constitutional limits—cannot be taken for granted due to the existence of competing forms of government that appear ...
Law, David S.
core +1 more source
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
The Relationship of Rejection Sensitivity to Depressive Symptoms in Adolescence: The Indirect Effect of Perceived Social Acceptance by Peers. [PDF]
Behav Sci (Basel), 2023 Giovazolias T.
europepmc +1 more source
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
EnergiesGiven that the implementation of renewable technologies has some key bottlenecks in adoption, this topic has been explored. Particularly, we are reviewing existing theories and models to understand their fit for changing social structures and evolving ...
Tanvi Bhatia +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source