Results 121 to 130 of about 436,469 (302)

Social Inclusion of Immigrant Irish Primary School Children: Urbanicity, School Size and School Composition

open access: yesSocial Sciences
Given world immigration patterns, understanding immigrant children’s social inclusion is crucial, especially the role of school characteristics.
Martin H. Jones   +6 more
doaj   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

open access: yesMolecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy   +10 more
wiley   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Culture, demography and individuals' technology acceptance behaviour: A PLS based structural evaluation of an extended model of technology acceptance in South-Asian country context

open access: yes, 2011
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.The models that predict the factors of individuals’ acceptance behaviour are predominantly based on a technology acceptance model (TAM) or the TAM’s ...
Abbasi, Muhammad Shariif
core  

Spam Detection in Social Networks based on Peer Acceptance

open access: yes, 2020
Online Social Networks (OSNs) have become immensely popular for spammers spreading malicious content and links. Using the nature of OSNs, spammers frequently change their behavior to avoid detection.
Ernest Foo   +5 more
core   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

open access: yesMolecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi   +14 more
wiley   +1 more source

Do TV Watching and Gaming Affect Adolescents’ Social Acceptance Among Classmates?

open access: yesYouth
Social acceptance among peers is an important predictor of adolescents’ academic and social outcomes. This study investigates how social acceptance depends on adolescents’ engagement in watching TV and gaming. Based on Contact Theory, we expected that TV
Verena Hofmann   +3 more
doaj   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

Diverse families: Challenges and social acceptance

open access: yesRevista de Ciencias Sociales
The family is a social institution that has evolved by adapting to diversity and reflecting historical, economic, cultural, geographic, and political changes.
Yuly Inés Liñán Cuello   +2 more
doaj   +1 more source

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