Results 131 to 140 of about 436,469 (302)

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Acceptance of Inequality in the Social Democratic Welfare State : Income Differences, Welfare Chauvinism, and Populism in Sweden

open access: yes
The study examines two dimensions of inequality acceptance in Sweden—income differences and welfare chauvinism—as well as their association with populist attitudes.
Lindh, Arvid
core   +1 more source

Social Acceptance of Greywater Reuse in Rural Areas. [PDF]

open access: yesJ Environ Public Health, 2022
Al-Khatib IA   +3 more
europepmc   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

open access: yesMolecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht   +3 more
wiley   +1 more source

The role of acceptance and job control in mental health, job satisfaction, and work performance

open access: yes, 2003
Acceptance, the willingness to experience thoughts, feelings and physiological sensations without having to control them or let them determine one's actions, is a major individual determinant of mental health and behavioral effectiveness in a more recent
Bunce, David, Bond, Frank W.
core   +1 more source

Public Perceptions and Social Acceptance of Renewable Energy Projects in Epirus, Greece: The Role of Education, Demographics and Visual Exposure

open access: yesWorld
The social acceptance of Renewable Energy Sources (RESs) is a decisive factor in the successful implementation of clean energy projects. This study explores the attitudes, demographic profiles, and common misconceptions of citizens in the Region of ...
Evangelos Tsiaras   +2 more
doaj   +1 more source

Mediators of Social Acceptance Among Emerging Adult Survivors of Childhood Cancer. [PDF]

open access: yesJ Adolesc Young Adult Oncol, 2023
Crowder SL   +5 more
europepmc   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

Physiological measurements in social acceptance of self driving technologies. [PDF]

open access: yesSci Rep, 2022
Palatinus Z   +11 more
europepmc   +1 more source

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