Results 111 to 120 of about 12,529,564 (274)

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

open access: yesMolecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu   +3 more
wiley   +1 more source

Demographic differences and internet banking acceptance [PDF]

open access: yes, 2011
This research contributes to additional understanding of TAM’s validity in Internet banking acceptance. Although some user profile variables have been examined in technology acceptance research, there has been little research investigating the new roles ...
Li, Honglei, Lai, Min Mei
core  

Public Perceptions and Social Acceptance of Renewable Energy Projects in Epirus, Greece: The Role of Education, Demographics and Visual Exposure

open access: yesWorld
The social acceptance of Renewable Energy Sources (RESs) is a decisive factor in the successful implementation of clean energy projects. This study explores the attitudes, demographic profiles, and common misconceptions of citizens in the Region of ...
Evangelos Tsiaras   +2 more
doaj   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

open access: yesMolecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla   +4 more
wiley   +1 more source

Relationship between locus of control (internal, external) and "A" and "B" personality types with the social acceptance among substance abusers

open access: yesمجله علوم روانشناختی, 2015
The purpose of this study was to investigate the relationship between locus of control (internal, external), and "A" and "B" personality types with social acceptance among substance abuser of substance abuse treatment centers in Kermanshah.
Saeed Askari   +2 more
doaj  

Psychosocial Barriers and Social Perceptions in Oncology Patients with Tracheostomy: Case–Control Study

open access: yesCurrent Oncology
Patients with respiratory tract malignancies who undergo tracheostomy often experience profound psychosocial challenges related to visible anatomical changes and altered communication.
Tomasz Jurys   +5 more
doaj   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

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