Results 101 to 110 of about 1,770,192 (303)

Theory of social adaptation [PDF]

open access: yes, 2017
Дан анализ взглядов классиков социологии Э. Дюркгейма, М. Вебера, Т. Парсонса, Э. Тоффлера и Р. Мѐртона по проблеме социальной адаптации.Отмечено, что социальная адаптация, с одной стороны, является синонимом термину «социализация», а с другой стороны ...
Rizhenko, P., Рыженко, П. С.
core  

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Balancing expenditures on mitigation of and adaptation to climate change : an exploration of Issues relevant to developing countries [PDF]

open access: yes
Although climate policies have been so far mostly focused on mitigation, adaptation to climate change is a growing concern in developed and developing countries. This paper discusses how adaptation fits into the global climate strategy, at the global and
Lecocq, Franck, Shalizi, Zmarak
core  

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Adaptation and mitigation in long-term climate policies [PDF]

open access: yes
The paper analytically explores the optimal policy mix between mitigation and environmental adaptation against climate change at a macroeconomic level.
Brechet, Thierry   +2 more
core  

The OER FLOW and social media [PDF]

open access: yes, 2012
This presentation introduces some strategies for producing, sharing and reusing OER through the OER Flow and social media. The aim of this investigation is to identify how colearners can apply the OER Flow and social media to make the production and ...
Leslie, Scott, Okada, Alexandra
core  

Adaptation to Social Complexity

open access: yesMGIMO Review of International Relations, 2013
Modern Society as a Complex Dynamic System is Affected by Unforeseen Fluctuations. By Historical Standards, the Recent Introduction of the Nonlinear Approach into the Scientific World Picture put the Classical Understanding of Space and Time to the Obstruction.
openaire   +3 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

open access: yesMolecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli   +7 more
wiley   +1 more source

Increasing the level of adaptability of students through involvement in the activities of the student sports club [PDF]

open access: yesФизическое воспитание и студенческий спорт
Under the conditions of changing social environment, first-year students of higher education institutions are at risk of stress, as well as entering antisocial groups. Since they have to adapt to the new social and educational environment, it can have an
Zhdanovich, Dmitry O.   +4 more
doaj   +1 more source

Home - About - Disclaimer - Privacy