Results 121 to 130 of about 409,513 (309)

Decision-making for climate change adaptation: A systems thinking approach [PDF]

, 2013
The impacts of climate change are exacerbated by inefficient adaptation and mitigation decision making, due to the complexity of the decision-making environment. As a consequence, there is no single approach to planning and decision making.
Kambiz Maani, Maani, Kambiz
core  

Everyday realities of climate change adaptation in Mozambique

, 2012
This paper analyzes discourses and practices of flood response and adaptation to climate change in Mozambique. It builds on recent publications on climate change adaptation that suggest that the successes and failures of adaptation highly depend on the ...
Hilhorst, Dorothea, Artur, Luis, Hilhorst, D.J.M., Artur, L.   +3 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

The Classic-Novel Adaptation from 1995 to 2009 [PDF]

, 2010
This thesis explores the dynamic relationship between the nineteenth-century novel and the screen, interrogating evolving trends in film and television adaptation from the mid-1990s to 2009.
WHITE, REBECCA,ARWEN
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Extreme heat and climate change: adaptation in culturally and linguistically diverse (CALD) communities [PDF]

, 2013
Background: Several overseas studies have identified that people in ethnic minority groups are at greater risk during heatwaves. However, there is a paucity of information on this issue in Australia.
Peng Bi, Alana Hansen, Arthur Saniotis
core  

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Building a Model of Social and Psychological Adaptation

SSRN Electronic Journal, 2017
The paper presents a model for social and psychological assistance to militaries discharged of service and the members of their families through the example of Bulgaria which has the potential to be a basis for the creation of an adaptive program and setting up criteria for efficiency in it.
openaire   +4 more sources

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Increasing the level of adaptability of students through involvement in the activities of the student sports club [PDF]

Физическое воспитание и студенческий спорт
Under the conditions of changing social environment, first-year students of higher education institutions are at risk of stress, as well as entering antisocial groups. Since they have to adapt to the new social and educational environment, it can have an
Zhdanovich, Dmitry O., Kartavy, Sergey V., Osten, Vera A., Romanov, Sergey S., Filipeva, Diana Dmitrievna   +4 more
doaj   +1 more source