Results 121 to 130 of about 1,770,192 (303)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Life Domain Research Report Series: School and Employment [PDF]

open access: yes, 2008
The Life Domain Series describes the community adaptation of children and youth graduating from residential and intensive family service children’s mental health programs in multiple life domains (education and work, social involvements, family and ...
Cameron, Gary   +3 more
core   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

SOCIAL-PSYCHOLOGICAL ADAPTATION IN ORGANIZATIONS OF PERM NETWORK BUSINESS

open access: yesВестник университета, 2019
The article deals with actual problems of workers' adaptation in the conditions of modern network business organizations as one of the elements of the application of a scientific approach for the growth of labor productivity.
V. Levchenko, E. Zykovа
doaj  

An assessment tool and integrated index for sustainable oil palm production [PDF]

open access: yes, 2010
Many prominent sectors of the international agricultural commodities market have been calling upon their stakeholders to define and implement social responsibility and sustainability benchmarks, aiming at product quality and production practices ...
Caliman, Jean-Pierre   +2 more
core  

Analytical reasoning task reveals limits of social learning in networks

open access: yes, 2014
Social learning -by observing and copying others- is a highly successful cultural mechanism for adaptation, outperforming individual information acquisition and experience.
Ariely D   +13 more
core   +2 more sources

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Four major task domains of science for sustainability [PDF]

open access: yes
We propose a research agenda integrating environment-related science, technology, and innovation (STI) using a problem-solving approach to sustainable development.
Jappe-Heinze, Arlette
core  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Distribution and duration of chores in married couple households

open access: yesСоциологическая наука и социальная практика
Based on data from the “Russian Longitudinal Monitoring Survey” ( RLMS-HSE), this article analyzes the gender distinctions and tendencies that characterize changes in the structure of how chores are assigned, and how much time is allocated to them, in ...
Polina M. Kozyreva   +2 more
doaj   +1 more source

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