Results 131 to 140 of about 1,770,192 (303)
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Climatic system as constituent of naturally- resource potential of economy [PDF]
, 2007 Social and ecological and economic consequences and damage, related to the change of climate require making of taking measures on adaptation to these changes and softening of their consequences, that will allow economic to ground made decisions on the ...
Telepenko, Irina
core
Doubly Adaptive Social Learning
In social learning, a network of agents assigns probability scores (beliefs) to some hypotheses of interest, which rule the generation of local streaming data observed by each agent. Belief formation takes place by means of an iterative two-step procedure where: i) the agents update locally their beliefs by using some likelihood model; and ii) the ...
Carpentiero, Marco +3 more
openaire +2 more sources
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Framing adaptation in the Victorian context: synthesis report [PDF]
This synthesis report provides a summary of the research activity and conveys the key findings arising from the 18 month ‘Framing Adaptation in the Victorian Context’ project undertaken between 2010 and 2012.
Darryn McEvoy, Hartmut Funfgeld
core
International Journal of Research in Social Science and HumanitiesThis research aims to describe and analyze the reality of changes in social behavior that occur in the Nepal Van Java Tourism Village area, as well as describe and analyze the forms of social adaptation of the community in connection with the reality of changes in social behavior in the Nepal Van Java Tourism Village area.
Riyadi Kaunaen +2 more
openaire +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
NWIG, 2009 This article examines the readjustment and remigration of ex-indentured Indian laborers from India to the Caribbean. The author shows that there was a small but steady influx of ex-indentured Indian laborers or second-term Indian migrants to the ...
Lomarsh Roopnarine
doaj
The neurocognitive impact of loneliness and social networks on social adaptation. [PDF]
Sci Rep, 2023 Franco-O'Byrne D +9 more
europepmc +1 more source