Results 141 to 150 of about 409,513 (309)

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Adaptation and Development: Whose Goals and Priorities Count?

open access: yes, 2010
It has been argued that adaptation to climate change should be integrated with development activities, and that it is time to pursue its 'mainstreaming' within such programmes (Burton 2009).
Nalau, Johanna, Heyd, T.
core  

Creating a climate for food security: the business, people & landscapes in food production [PDF]

open access: yes, 2013
Balancing human and environmental needs is urgent where food security and sustainability are under pressure from population increases and changing climates.
Nazrul Islam   +2 more
core  

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Perceived social support and community adaptation in schizophrenia

open access: yes, 1998
Prompted by the continuing transition to community care, mental health nurses are considering the role of social support in community adaptation. This article demonstrates the importance of distinguishing between kinds of social support and presents ...
Clinton, M.   +4 more
core   +1 more source

SOCIAL-PSYCHOLOGICAL ADAPTATION IN ORGANIZATIONS OF PERM NETWORK BUSINESS

open access: yesВестник университета, 2019
The article deals with actual problems of workers' adaptation in the conditions of modern network business organizations as one of the elements of the application of a scientific approach for the growth of labor productivity.
V. Levchenko, E. Zykovа
doaj  

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Adapting the community sector for climate extremes [PDF]

open access: yes, 2013
 People experiencing poverty and inequality will be affected first and worst by the impacts of climate change to infrastructure and human settlements, including those caused by increasingly frequent and intense extreme weather events and natural ...
Karl Mallon   +4 more
core  

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Distribution and duration of chores in married couple households

open access: yesСоциологическая наука и социальная практика
Based on data from the “Russian Longitudinal Monitoring Survey” ( RLMS-HSE), this article analyzes the gender distinctions and tendencies that characterize changes in the structure of how chores are assigned, and how much time is allocated to them, in ...
Polina M. Kozyreva   +2 more
doaj   +1 more source

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