Results 151 to 160 of about 12,916,776 (308)
A framework for adaptation of Australian households to heat waves [PDF]
, 2013 Climate change is leading to an increased frequency and severity of heat waves. Spells of several consecutive days of unusually high temperatures have led to increased mortality rates for the more vulnerable in the community. The problem is compounded by
John Boland, Stephen Pullen, Wasim Saman
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NWIG, 2009 This article examines the readjustment and remigration of ex-indentured Indian laborers from India to the Caribbean. The author shows that there was a small but steady influx of ex-indentured Indian laborers or second-term Indian migrants to the ...
Lomarsh Roopnarine
doaj
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Behavioral SciencesFamily structures are diverse, with single-parent families being special. Single-parent families have garnered interest regarding their impact on their children’s development in relation to gender roles and social adaptation.
Yunping Song +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Preface: Adaptation in social and semantic web
, 2010 The Adaptation in Social and Semantic Web workshop analyzes the benefits adaptation and personalization have to offer within the current Web and the Web of the future, and the numerous open challenges, putting together the Semantic Web, Social Web and ...
TASSO, Carlo +5 more
core +1 more source
ESCAPISM AS THE DEVIATION IN THE YOUTH'S SOCIALIZATION
Вестник Кемеровского государственного университета, 2013 In article the main sociological approaches to the phenomenon of escapism are considered. The connection of es capism with the processes of society marginalization is shown.
N. V. Nyatina
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Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Adapting the community sector for climate extremes [PDF]
, 2013 People experiencing poverty and inequality will be affected first and worst by the impacts of climate change to infrastructure and human settlements, including those caused by increasingly frequent and intense extreme weather events and natural ...
Karl Mallon +4 more
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