Results 161 to 170 of about 409,513 (309)

Institutional governance barriers for the development and implementation of climate adaptation strategies

, 2009
In this paper we summarise the main social barriers to adaptation presented in climate literature – the inherent uncertainty of climate change, fragmentation, institutional voids, short term horizon of politicians and policies, and the motives and ...
Termeer, C.J.A.M., Klostermann, J.E.M., Biesbroek, G.R., Kabat, P.   +3 more
core  

Climate change in the healthcare and social welfare sector : Climate change adaptation plan of Ministry of Social Affairs and Health (2021–2031)

, 2021
Climate change affects people’s health and wellbeing in Finland both directly and indirectly. It is important to be prepared for variations in the weather and climate and for extreme weather and climate conditions and their effects even in the current ...
Tuomisto, Jouni, Hemminki, Elina, Viljamaa, Seija, Huldén, Lena, Mäkelä, Henna, Sarlio, Sirpa, Mukala, Kristiina, Paunio, Mikko, Karvonen, Sakari, Lyyra, Krista, Mänttäri, Satu, Virtanen, Suvi, Voutilainen, Liina, Halonen, Jaana, Raulio, Susanna, Kangas, Pauliina, Partonen, Timo, Huusko, Sari, Keskimäki, Ilmo, Meriläinen, Päivi, Viitanen, Anna-Kaisa, Kollanus, Virpi, Kuusipalo, Heli, Koivula, Riitta   +23 more
core  

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Aboriginal responses to climate change in arid zone Australia [PDF]

, 2013
Given the broad scale and fundamental transformations occurring to the natural environment due to anthropogenic climate change in the present era, what does the future hold for Aboriginal people in remote arid regions of Australia?  In searching for
Brian Head, Paul Memmott, Joseph Reser
core  

Effect of Intergenerational Trends on Parental Child-Rearing Gender Role Attitudes (PCGAs) in Single-Parent Families: A Relative Mediation

Behavioral Sciences
Family structures are diverse, with single-parent families being special. Single-parent families have garnered interest regarding their impact on their children’s development in relation to gender roles and social adaptation.
Yunping Song, Mengping Yang, I-Jun Chen, Saba Ponam, Ying Shi   +4 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Preface: Adaptation in social and semantic web

, 2010
The Adaptation in Social and Semantic Web workshop analyzes the benefits adaptation and personalization have to offer within the current Web and the Web of the future, and the numerous open challenges, putting together the Semantic Web, Social Web and ...
TASSO, Carlo, AND J. VASSILEVA EDS, F. CENA, S. KLEANTHOUS, DATTOLO, Antonina, D. BUENO VALLEJO   +5 more
core  

ESCAPISM AS THE DEVIATION IN THE YOUTH'S SOCIALIZATION

Вестник Кемеровского государственного университета, 2013
In article the main sociological approaches to the phenomenon of escapism are considered. The connection of es capism with the processes of society marginalization is shown.
N. V. Nyatina
doaj  

The neurocognitive impact of loneliness and social networks on social adaptation. [PDF]

Sci Rep, 2023
Franco-O'Byrne D, Sepúlveda JPM, Gonzalez-Gomez R, Ibáñez A, Huepe-Artigas D, Matus C, Manen R, Ayala J, Fittipaldi S, Huepe D.   +9 more
europepmc   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source