Results 181 to 190 of about 1,770,192 (303)

Adapting to an ageing society [PDF]

In 2050 the global population aged over 60 will reach two billion, making this age group three times larger than it was in 2000. This is a challenge that is facing both mature and emerging economies.
Simon Biggs
core  

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Effects of the sport education model on table tennis skills, sport motivation, and social adaptation in high school students. [PDF]

Front Psychol
Tang J, Chen X, Wang H.
europepmc   +1 more source

Research on the relationship between physical activity, sleep quality, psychological resilience, and social adaptation among Chinese college students: A cross-sectional study. [PDF]

Front Psychol, 2023
Li Y, Guo K.
europepmc   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

The temporal relationship between social adaptation and depression: based on cross-lagged network analysis. [PDF]

BMC Psychol
Li X, Zhang J, Pan J, Xu H, Wen X.
europepmc   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

How depression affects school social adaptation: the mediating role of sleep quality and the buffering effect of physical activity. [PDF]

Front Sports Act Living
Chen C, Liu K, Zhou Z.
europepmc   +1 more source

The Relationship between Physical Activity and College Students' Mobile Phone Addiction: The Chain-Based Mediating Role of Psychological Capital and Social Adaptation. [PDF]

Int J Environ Res Public Health, 2022
Chen H, Wang C, Lu T, Tao B, Gao Y, Yan J.   +5 more
europepmc   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source