Results 191 to 200 of about 12,916,776 (308)

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Social Adaptation to Change in Peer Behavior Before and After a Pilot Randomized Clinical Trial of a Theatre-Based Intervention for Adults With Autism. [PDF]

J Autism Dev Disord
Muscatello RA, Klemencic ME, Calvosa R, Corbett BA.   +3 more
europepmc   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Physical activity and social adaptation in high school students: the chain mediating roles of interpersonal relationships and psychological resilience. [PDF]

Front Public Health
Chen Y, Ma J, Li J, Zang Y.
europepmc   +1 more source

The impact of loneliness and social adaptation on depressive symptoms: Behavioral and brain measures evidence from a brain health perspective. [PDF]

Front Psychol, 2023
Franco-O Byrne D, Gonzalez-Gomez R, Morales Sepúlveda JP, Vergara M, Ibañez A, Huepe D.   +5 more
europepmc   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Internet addiction and social adaptation among adolescents: the chain mediation effects of peer relationships and self-identity. [PDF]

BMC Psychol
Liao X, Yin L, Li Y, Wang Y.
europepmc   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source

The Effects of Physical Exercise on the Social Adaptation of Older Adults-With Reference to the Mediating Effect of Aging Identity. [PDF]

Behav Sci (Basel)
Zhang Z, Zhang J, Fu C, Fan C.
europepmc   +1 more source

Effect of the personality traits of healthy Japanese workers on depressive symptoms and social adaptation, and on the achievement rate of exercise therapy to prevent major depression. [PDF]

Front Psychol, 2023
Ikenouchi A, Okamoto N, Matsumoto T, Yoshimura R.   +3 more
europepmc   +1 more source