Results 141 to 150 of about 1,488,006 (306)

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

The social adjustment of patients with schizophrenia: implications to the mental health policy in Brazil

open access: yesRevista de Saúde Pública
A sample (n=124) of schizophrenic patients from a defined catchment area of the city os S.Paulo, Brazil, who had been consecutively admitted to hospital, was assessed for psychopathological status and social adjustment levels.
Paulo R. Menezes, Anthony H. Mann
doaj  

Social Adjustment in Mothers of Children with Gender Identity

open access: yesJournal of Mazandaran University of Medical Sciences, 2017
Background and purpose: Gender dysphoria is a disorder that causes problems for families and societies. This research compared the level of social adjustment between mothers of transgender children and mothers of normal children.
Mahnaz Mozaffaripour   +2 more
doaj  

MEASURES AND INSTRUMENTS USED AS A RESPONSE TO CRISES IN EUROPEAN UNION - AN OVERVIEW [PDF]

open access: yes
During latest times, financial crises have been a common occurrence in emerging market (and transition) countries with negative influence for the economies.
FIRTESCU BOGDAN
core  

Cognitive and Interpersonal Factors Affecting Social Adjustment of University Students in Pakistan. [PDF]

open access: yesInt J Environ Res Public Health, 2022
Kayani S   +4 more
europepmc   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

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