The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Direct versus indirect standardization in risk adjustment. [PDF]
Direct and indirect standardization procedures aim at comparing differences in health or differences in health care expenditures between subgroups of the population after controlling for observable morbidity differences.
Schokkaert, Erik, van de Voorde C,
core
Adolescent leisure reading and its longitudinal association with prosocial behavior and social adjustment. [PDF]
Lenhart J, Richter T, Appel M, Mar RA.
europepmc +1 more source
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Comparision the effectiveness of cognitive behavioral therapy and acceptance and commitment therapy on social adjustment of adolescents with social anxiety disorder [PDF]
Background and aims: Due to its nature, social anxiety can disturb the social adjustment of adolescents. The purpose of this study was to compare the effectiveness of cognitive behavioral therapy (CBT) and acceptance and commitment therapy (ACT) on the ...
Fatemeh Shariati, Majid Pourfaraj
doaj
Comparing the Impacts of Social Security Benefit Reductions on the Income Distribution of the Elderly [PDF]
Benefit reductions will likely be a part of the eventual Social Security reform in the United States. This research attempts to quantify the intragenerational and intergenerational impacts of different benefit reduction proposals on the incomes of the ...
Pfau, Wade Donald
core +1 more source
The subjective assessment of work and social adjustment impairments and associated psychopathologies in Japanese adult female patients with anorexia nervosa. [PDF]
Iida N, Ono J, Mizuhara Y, Narumoto J.
europepmc +1 more source
AAA+ protein unfoldases—the Moirai of the proteome
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
Financial Globalization and Labor: Employee Shareholding or Labor Regression? [PDF]
The authors review from a critical perspective the ‘patrimonial capitalism’ approach, as well as its analysis of wage-labor transformations in developed economies during the last thirty years.
Bibiana Medialdea García +1 more
core
Social avoidance and social adjustment in Chinese preschool migrant children: the moderating role of teacher-child relationships. [PDF]
Zhu J, Yin X, Li X, Dong X, Zou S, Li Y.
europepmc +1 more source

