Results 111 to 120 of about 1,488,006 (306)
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Effect of Inclusion of Hard of Hearing Students in Regular Schools on Their Social Adjustment [PDF]
Ravānshināsī-i Afrād-i Istis̠nāyī, 2014 This study compared social adjustment of hard of hearing students included in regular schools of Shahrekord and those enrolled in the city’s exceptional schools from the viewpoint of their teachers and parents.
Qodratollah Jahani
doaj
Designing incenttives in local public utilities, an international comparison of the drinking water sector [PDF]
Direct and indirect standardization procedures aim at comparing differences in health or differences in health care expenditures between subgroups of the population after controlling for observable morbidity differences.
Kristof De Witte, Rui C. Marques
core
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Adjustment of fifth grade social studies material on Mexico for children reading below grade level [PDF]
, 1961 Thesis (Ed.M.)--Boston ...
Wernick, Gertrude M., Young, Eleanor R.
core +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Magic as a tool to build rapport with new environment: Herr Röslein trilogy by Silke Lambeck
RUDN Journal of Studies in Literature and JournalismInvestigates how a literary character adapts to a new context in the debut trilogy of the German writer Silke Lambeck ( Herr Röslein , 2007; Herr Röslein kommt zurück , 2008; Wo bleibt Herr Röslein? 2010).
Yuliya V. Krasovickaya
doaj +1 more source
World Bank treatment of the social impact of adjustment programs [PDF]
Since 1987 the Bank's operational guidelines have required President's Reports supporting structural adjustment loans (SALs) to pay particular attention to an analysis of the short term impact of the adjustment program on the poor and to measures ...
Carvalho, Soniya, Ribe,Helena
core
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source