Results 121 to 130 of about 327,713 (218)

Negative parenting styles and social adjustment of university students: a moderated chain mediation model. [PDF]

Curr Psychol, 2022
Xu C, Yan W.
europepmc   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

The relationship between physical activity and social adjustment in adolescents: the longitudinal mediating role of emotional resilience. [PDF]

BMC Public Health
Yu X, Wu M, Wang J, Yang Y, Qiu Q, Yuan Y, Li X.   +6 more
europepmc   +1 more source

Callous-Unemotional Traits and Social Adjustment among Chinese Preschoolers: The Moderating Role of Teacher-Child Relationship. [PDF]

Int J Environ Res Public Health, 2023
Zhu J, Xia X, Wu Q, Zou S, Li Y.
europepmc   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

Distinct patterns of parental involvement in Chinese families and preschoolers' social adjustment. [PDF]

Front Psychol
Wu Z, Zhang D, Chen L, Chen L, Zhang W.
europepmc   +1 more source

Experience of annual events in the family and social adjustment of school-age children. [PDF]

Child Adolesc Psychiatry Ment Health, 2022
Hosokawa R, Katsura T, Taira K.
europepmc   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Viewing Teens as Responsible in Family: Implications for Chinese Youth's Academic and Social Adjustment. [PDF]

Child Dev
Yang B, Zhou Z, Devakonda V, Chen BB, Qu Y.   +4 more
europepmc   +1 more source

Aggressive and Defensive Behaviour, Normative, and Social Adjustment in the Complex Dynamics of School Bullying. [PDF]

Psychosoc Interv, 2023
Carmona-Rojas M, Ortega-Ruiz R, Romera E, Bravo A.   +3 more
europepmc   +1 more source