Results 91 to 100 of about 842,366 (296)

Remote Magnetomechanical Neuromodulation Uncovers Therapeutic Mechanisms for Alleviating Parkinsonian Symptoms in Freely Moving Mice

Advanced Science, EarlyView.
Magnetomechanical neuromodulation using magnetic nanodiscs enables remote activation of neurons. In a hemiparkinsonian mouse model, alternating magnetic fields actuate the nanodiscs to generate torque that opens mechanosensitive ion channels within the subthalamic nucleus, thereby modulating basal ganglia motor circuitry.
Anouk Wolters, Lorenzo Signorelli, Christian Herff, Sophia Gimple, Renzo Riemens, Gunter Kenis, Kim Rijkers, Hamed Shabani, Jyh‐Jang Sun, Yasin Temel, Hans Clusmann, Danijela Gregurec, Sarah‐Anna Hescham   +12 more
wiley   +1 more source

Narrative Review of Social Anxiety Disorder [PDF]

Taḥqīqāt-i ̒Ulūm-i Raftārī
Aim and Background: Social anxiety is one of the most common psychological disorders, especially among students. This disorder, which is related to the fear of negative evaluation by others, can have negative effects on social relationships, academic ...
Nooshin Mansoori, Mustafa Bolghan-Abadi
doaj  

Social Anxiety Disorder: A General Overview [PDF]

SHS Web of Conferences
Social anxiety disorder (SAD) is a branch of anxiety disorder, known as the major anxiety disorder that is neglected the most. Patients with SAD will try to avoid social situations, feeling embarrassed and stressed.
Guan Yongxin
doaj   +1 more source

Palatable‐Food–Driven Top‐Down Circuit Inhibits PVNCRF Activity to Mitigate Stress Via Peri‐PVNCRFR1 Neurons

Advanced Science, EarlyView.
Palatable food alleviates stress and prevents anxiety. This study uncovers a dedicated neural pathway: dopamine release in the PFC activates D1R neurons, whose projections to the peri‐PVN engage a population of anxiolytic CRFR1 neurons. These neurons then inhibit stress‐induced hyperactivity of PVNCRF neurons, providing a circuit‐level explanation for ...
Yuchuan Hong, Shirui Jun, Tianjiao Deng, Gaojie Shao, Dan Liu, Yi Sun, Yan Chen, Qian Xiao, Jie Shao, Sheng Wang, Tianwen Huang, Fan Yang, Jie Tu   +12 more
wiley   +1 more source

Personality and anxiety disorders: examination of revised reinforcement sensitivity theory in clinical generalized anxiety disorder, social anxiety disorder, and panic disorder

Current Issues in Personality Psychology, 2020
Behrooz Afshari
doaj   +1 more source

Self-processing characteristics from first-person and third-person perspectives in individuals with social anxiety disorder: insights into negative bias

Frontiers in Psychiatry
BackgroundAs one of the most common psychological problems, social anxiety disorder (SAD) has lots of negative effects on the physical and mental development of individuals, such as decreasing the quality of interpersonal relationships, and even causing ...
Huating Wu, Caizhen Yue, Fasheng Cao, Yihong Long, Yihong Long, Yan Wang, Yan Wang   +6 more
doaj   +1 more source

Psychological and pharmacological interventions for social anxiety disorder in adults: a systematic review and network meta-analysis

Lancet psychiatry, 2014
Summary Background Social anxiety disorder—a chronic and naturally unremitting disease that causes substantial impairment—can be treated with pharmacological, psychological, and self-help interventions.
E. Mayo-Wilson, S. Dias, Ifigeneia Mavranezouli, Kayleigh Kew, D. Clark, A. Ades, S. Pilling   +6 more
semanticscholar   +1 more source

Long‐Term Ambient Benzene Exposure and Brain Disorders Among Urban Adults: Effect Modification by Genetic Susceptibility and Potential Mediation by Plasma Proteins

Advanced Science, EarlyView.
Low‐level ambient benzene exposure is associated with increased risks of multiple brain disorders in urban adults. Genetic susceptibility modifies these associations, while plasma proteomics points to potential biological pathways linking benzene exposure to adverse brain health.
Jianhui Guo, Xia Zhong, Petros Koutrakis, Carolina L. Zilli Vieira, Feifei Si, Yaqi Wang, Xinyao Lian, Yi Fan, Zhaokun Wang, Shaodan Huang, Jing Li   +10 more
wiley   +1 more source

Social anxiety disorder: A review of environmental risk factors

Neuropsychiatric Disease and Treatment, 2008
Christina A Brook, Louis A SchmidtDepartment of Psychology, Neuroscience and Behaviour, McMaster University, Hamilton, Ontario, CanadaAbstract: Social anxiety disorder (SAD) is a debilitating and chronic illness characterized by persistent fear of one or
Christina A Brook, Louis A Schmidt
doaj  

Pharmacological Inhibition of FKBP51 Mitigates Early Life Adversity‐Induced Social Deficits in Male Mice

Advanced Science, EarlyView.
Early life adversity triggers persistent social subordination and brain‐wide molecular dysregulation. Pharmacological inhibition of the stress‐mediator FKBP51 during the adversity period prevents these long‐term deficits and restores normative social hierarchy.
Joeri Bordes, Xiuqi Ji, Serena Gasperoni, Choham Sudre‐Chinsky, Amirali Kalbasi, Daniela Harbich, Cornelia Flachskamm, Paula Fontanet, Sowmya Narayan, Manfred Uhr, Christian Namendorf, Camilla Bellone, Alon Chen, Felix Hausch, Juan Pablo Lopez, Mathias V. Schmidt   +15 more
wiley   +1 more source