Results 91 to 100 of about 787,562 (301)
Examining the symptom-level specificity of negative problem orientation in a clinical sample [PDF]
, 2014 This article was originally published in Cognitive Behaviour Therapy. The version of record can be found here: http://www.tandfonline.com/doi/abs/10.1080/16506073.2014.987314Given the equivocal state of the literature as to the symptom-level specificity ...
Fergus, Thomas A. +3 more
core +2 more sources
Advanced Materials, EarlyView.A nano‐interception strategy disrupts pathogenic fibroblast–macrophage crosstalk in chronic heart failure. Scalable Prussian blue nanoparticles selectively sequester CCL2 via ultrahigh‐affinity binding, preventing CCR2+ macrophage recruitment and breaking a key fibro‐inflammatory circuit. This approach demonstrates robust efficacy in murine and porcine
Bo Chen +16 more
wiley +1 more source
PTSD, depression, and anxiety among Palestinian women victims of domestic violence in the Gaza Strip [PDF]
, 2015 Background: Domestic violence is a universal phenomenon which affects all family members and specially children and women. Common reactions to domestic violence are post-traumatic stress disorder, depression, and anxiety.
Tawahina, Ahmad Abu +3 more
core +1 more source
Enhancing Small Molecule Sensing With Aptameric Functionalized Nano Devices
Advanced Materials Technologies, EarlyView.Unveiling an ultra‐sensitive, non‐invasive neurotransmitter sensor. For the first time, a nanoscale sensor for detecting an important neurotransmitter was demonstrated using micro‐electromechanical systems (MEMS) technology. Our approach utilized field‐effect transistor (FET)‐based readout to enable pico‐molar detection of biomarkers in sweat.
Thi Thanh Ha Nguyen +11 more
wiley +1 more source
Optogenetic insights on the relationship between anxiety-related behaviors and social deficits [PDF]
, 2014 Many psychiatric illnesses are characterized by deficits in the social domain. For example, there is a high rate of co-morbidity between autism spectrum disorders and anxiety disorders.
Caitlin Miya Vander Weele +4 more
core +3 more sources
A Central Somatic Transmission Mediates Proprioceptive Facilitation of Muscle Pain
Advanced Science, EarlyView.Zhang et al. uncover a novel central mechanism for persistent muscle pain, in which TRPA1 sensitization in MeV proprioceptive neurons enhances somatic secretion. This, in turn, disinhibits descending pain control from neighboring noradrenergic locus coeruleus neurons via local GABAergic circuits, thereby promoting inflammatory muscle pain.
Xiaoyu Zhang +15 more
wiley +1 more source
Psychological treatment of social anxiety disorder: a meta-analysis. [PDF]
, 2009 Background Older meta-analyses of the effects of psychological treatments of social anxiety disorder have found that these treatments have moderate to large effects. However, these earlier meta-analyses also included non-randomized studies, and there are
A. van Straten +11 more
core +3 more sources
Paternal Circadian Disruption Impairs Offspring Cognition via Sperm microRNAs
Advanced Science, EarlyView.Paternal circadian disruption remodels the sperm small RNA payload, elevating miR‐92a‐3p/miR‐25‐3p levels and perturbing early embryonic gene regulatory programs. Microinjection experiments and single‐embryo transcriptomics reveal sex‐specific developmental vulnerabilities, ultimately impairing offspring hippocampal synaptic plasticity and cognition ...
Kexin Zou +22 more
wiley +1 more source
The inventory of callous–unemotional traits: psychometric properties among referred and non-referred portuguese female juveniles [PDF]
, 2017 The presence of callous-unemotional (CU) traits delineates a subgroup of male youth with severe conduct disorder and antisocial behavior, but little research has been done among female youth.
Gonçalves, Rui Abrunhosa +3 more
core +1 more source
Neuid: A Novel Neuron‐Enriched LncRNA that Connects Epigenetic Gene Silencing to Alzheimer's Disease
Advanced Science, EarlyView.ABSTRACT The increasing evidence that non‐coding RNAs can become deregulated during pathogenesis is dramatically expanding the space for drug discovery beyond the protein‐coding genome. Long noncoding RNAs (lncRNAs) are emerging as key regulators of cellular function, yet most remain uncharacterized.
Ranjit Pradhan +17 more
wiley +1 more source