Results 61 to 70 of about 1,424,287 (304)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

A cross-sectional study to determine the pattern, health-related problems and social aspects associated with alcohol use among adults of the rural population in Pune, Maharashtra

open access: yesMedical Journal of Dr. D.Y. Patil University, 2015
Background: The increasing production, distribution, promotion and easy availability of alcohol have resulted in alcohol-related problems emerging as a major public health concern.
Vijaykumar K More   +5 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Social aspects

open access: yes, 2009
Contains fulltext : 75842.pdf (Publisher’s version ) (Open Access)
Bijker, W.   +5 more
openaire   +2 more sources

Exploration of self-expression to improve L2 writing skills

open access: yesPer Linguam : A Journal of Language Learning, 2016
This article focuses on and explores the issue of teaching students to write with some level of fluency. In light of this, it investigates the use of expressive writing which can develop as the mainstay approach to help students improve their academic ...
Pfeiffer, Verbra Frances   +1 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

The local and street-level production of social citizenship. The case of Dutch Social Assistance

open access: yes, 2011
Much of the literature that analyses the impact of activation policies on the social citizenship of unemployed people focuses on the substantial aspects of these policies as these are regulated in national legislation. These analyses assume that national
UU LEG Research USG Public Matters   +6 more
core   +1 more source

The Necessity of Establishing a National Organization to Monitor and Enhance Women's Employability in the Water Transportation Sector [PDF]

open access: yesTransNav
The maritime transport industry is one of the most critical tradeways worldwide and has traditionally been a male stronghold, even as more and more women are admitted.
Anna Karadencheva   +2 more
doaj   +1 more source

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