Results 71 to 80 of about 1,424,287 (304)
Environmental and Climate Technologies, 2020 The Single Energy Sustainability Index combines three key sustainability indicators: environmental, social and economic. The use of indicators makes it possible to create an overall index that shows not only how green the region is, but also includes the
Slišāne Dzintra +3 more
doaj +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Ethical and social aspects of biotechnology Ethical and social aspects of biotechnology
Ubiquity, 2003 The globalisation of biotechnology brings not only new economic prospects but also new risks. The development of international bio-safety guidelines is essential.
openaire +2 more sources
Social progress index 2015 [PDF]
, 2015 The Social Progress Index, first released in 2014 building on a beta version previewed in 2013, measures a comprehensive array of components of social and environmental performance and aggregates them into an overall framework.
Social Progress Imperative
core
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
, 2005 Conversation analysis (CA) is now what Kuhn once called a normal science. It has a discernible body of concepts, methods, and recognizable objects of analysis.
McHoul, A.
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Social Culture : reevaluating the Paradigm [PDF]
, 2018 We can consider values as culturally objectified, abstract ideas of phenomena. Such ideas are of lasting significance to the satisfaction of needs of political subjects.
Hristić, Ljubomir
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Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Primary social and emotional aspects of learning (SEAL) small group interventions: a qualitative study of factors affecting implementation and the role of Local Authority support [PDF]
, 2009 The aims of the current study were to examine the factors affecting implementation of social and emotional aspects of learning (SEAL) small group interventions in primary schools and to explore the role of support from Local Authorities (LAs) in the ...
Michael Wigelsworth +11 more
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Social capital and the decline in HIV transmission - A case study in three villages in the Kagera region of Tanzania. [PDF]
, 2010 We present data from an exploratory case study characterising the social capital in three case villages situated in areas of varying HIV prevalence in the Kagera region of Tanzania. Focus group discussions and key informant interviews revealed a range of
Emmelin, M +14 more
core +1 more source