Results 101 to 110 of about 1,639 (298)
Why human connection is the true metric of research success
FEBS Open Bio, EarlyView.Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan +3 more
wiley +1 more source
Sociologie Românească, 2012 This article addresses the January 2012 protests from Bucharest, Romania. Due to protesters’ high social diversity, their numerous themes of discontent, and rejection of all current politicians, these protests have been compared to Spain’s „Indignados ...
Cătălin Augustin Stoica
doaj
YIPFα1A expression is regulated by multilayered molecular mechanisms
FEBS Open Bio, EarlyView.YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
The Tolerance as the Ethic Foundation of Social Economy into the Perspective of the Perspective of the “Included Third” in the Contextuality of Transmodernity [PDF]
Annals of Philosophy, Social and Human Disciplines, 2012 The tolerance is the form of the ethics, but the uninherent manifestation of the religious moralities, it developes socially profoundly, representing a pale projection of the christian ideal (challenge) of the principle of “love all people as you love ...
Antoniu Alexandru Flandorfer
doaj
FEBS Open Bio, EarlyView.The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer +7 more
wiley +1 more source
FEBS Open Bio, EarlyView.Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
Acute caffeine treatment protects the developing retina from ischemia‐induced cell death
FEBS Open Bio, EarlyView.Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento +6 more
wiley +1 more source
Social cohesion in the Russian society: Results of the empirical study
RUDN journal of SociologyThe article presents the results of the study of the perception of social cohesion in today’s Russia. The study consisted of two stages - expert and all-Russian - and was conducted with methods of expert assessments, focus groups and online survey in ...
V. A. Tupikova +2 more
doaj +1 more source
FEBS Open Bio, EarlyView.KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura +19 more
wiley +1 more source
College social insertion: an investigation based on the minimum social atom
, 2008 Ao longo da história, os deficientes ocupam um lugar de marginalização e sua inserção depende, em grande parte, do contexto social. Este trabalho se propôs a mapear as redes sociais de alunos universitários com deficiência física a partir de uma leitura psicodramática e identificar como o aluno avalia sua inserção a partir dos papéis desempenhados ...
Auad, Juliana Cal +1 more
openaire +2 more sources