Results 91 to 100 of about 1,639 (298)

Totalitarianism as a kind of culture of shame in the face of the «atomization» of society

open access: yes, 2013
В статті тоталітарна суспільна організація розглядається як така, що має свої витоки у первинних, родо-племінних формах соціалізації та постає як повернення до культури сорому, обумовленого суперечливим характером процесу атомізації та індустріалізації ...
Симоненко, С.П.   +1 more
core  

Neoliberalism and social-neighborhood networks. Experiences from Quito’s neighborhoods.

open access: yes
El presente trabajo expone la experiencia de intervención social en el Programa Barrios de Quito, bajo la Dirección de Vinculación con la Sociedad de la Universidad Central del Ecuador, durante el periodo académico 2022-2023. El objetivo es presentar las
Meneses Córdova, Gladys Carolina   +2 more
core   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

open access: yesFEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková   +3 more
wiley   +1 more source

Communication, Education and social movements online: New Imaginaries, old utopias

open access: yes, 2014
Due to the Internet arrival, the Social Movements, alternatives and critics, have considered it as a new scene capable to renew the traditional ways of intervention and collective action.
García-López, Marcial   +2 more
core  

From Patriotic Education to Militarist Indoctrination-Disciplinary Power and Silent Resistance in Russia after the Onset of the War against Ukraine

open access: yes
Since the beginning of Russia's war against Ukraine, various militaristic initiatives have been implemented in Russian schools. This article examines how teachers, pupils, and parents interpret state-driven patriotism amidst the war.
Alava, Jonna
core   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

open access: yesFEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee   +6 more
wiley   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

open access: yesFEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia   +3 more
wiley   +1 more source

The Atomization of Vulnerability: An Ethnographic Investigation of Quantification and Automation in Philadelphia's Homeless Services Coordinated Entry System

open access: yes
This dissertation is an ethnographic study of how data-driven governance has changed what it means to seek, and to provide, care in the US homeless services system.
Tracey, Pelle
core   +1 more source

Social ethics and individual morals / А. S. Laptenok [PDF]

open access: yes, 2015
В статье проводится мысль о том, что в современной культуре меняется соотношение индивидуальной и общественной морали. Происходит определенная атомизация морального пространства, которая приводит к изменению традиционных отношений в системе «индивид ...
Лаптенок, А. С.
core   +1 more source

Home - About - Disclaimer - Privacy