Results 81 to 90 of about 11,733,884 (255)

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

open access: yesMolecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim   +7 more
wiley   +1 more source

Communism – postcommunism continuum. The urban Romania in the 21st century

open access: yesSfera Politicii, 2013
While trying to understand the deeper meanings of the transition from communism to post communism in Romania, the study analyses the evolution of urban environment.
Tudor Pitulac
doaj  

The Role of the Value Basis in the Context of Waging Non-Kinetic Wars: Methodological Prerequisites for Analysis

open access: yesRUDN Journal of Political Science
The relevance of the topic presented in the article is determined primarily by the current foreign policy situation, namely the hybrid war unleashed by the collective West against the Russian Federation, a significant component of which are the so-called
Alexander V. Kurochkin
doaj   +1 more source

NETWORK CHARACTER OF INTERNATIONAL TERRORISM AND THE POSSIBILITY OF THE CONSOLIDATION OF THE RUSSIAN SOCIETY

open access: yesVestnik RUDN. International Relations, 2017
The purpose of this article is to analyze the network of the mechanism of reproduction of international terrorism - the phenomenon of post-truth, strongly modifies the previous interpretation of the political, ethnic, religious, cultural and social ...
А В Абрамов   +2 more
doaj   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani   +9 more
wiley   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

open access: yesMolecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico   +5 more
wiley   +1 more source

A comparison of diesel sprays CFD modeling approaches: DDM versus Sigma-Y Eulerian atomization model

open access: yes, 2016
[EN] A comparison between the Σ-Y atomization model and a classical DDM approach has been carried out for diesel spray CFD simulations. The Σ-Y model, originally proposed by Vallet and Borghi (1999), is based on an Eulerian representation of the spray ...
Pastor Enguídanos, José Manuel   +3 more
core   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

Recruitment Questionnaire 2024

open access: yes
Pseudonymized survey microdata from the 2024 Recruitment Questionnaire of The Social Study (TSS) — a probability-based panel survey of individuals aged 16+ residing in private households in Belgium.
The Social Study, TSS
core   +1 more source

Viscosity, Surface Tension, and Atomization of Water-Methanol and Diesel Emulsions

open access: yes, 2006
This article is the result of experimental studies of the rheologv, viscosities, surface tensions, and atomization of water-methanol and diesel emulsions.
Wei XL(魏小林)   +4 more
core   +1 more source

Home - About - Disclaimer - Privacy