Results 71 to 80 of about 13,064 (306)

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

[Review of the Book \u3ci\u3eAdvancing Theory in Labour Law and Industrial Relations in a Global Context\u3c/i\u3e] [PDF]

open access: yes, 1998
[Excerpt] The ideas and insights in Advancing Theory are an important contribution to the on-the-ground social justice movement challenging corporate rule in the global economy.
Compa, Lance A
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Is Liberalism the Problem? Review of Patrick Deneen, Why Liberalism Failed

open access: yes, 2018
A specter is haunting conservatism — the specter, indeed, of Marx. Those conservatives too young to remember the Cold War are increasingly suspicious of the economic and political prescriptions of the older anticommunism: capitalism as opposed to ...
McCullough, Ross W.
core  

An Efficient Streaming Algorithm for the Submodular Cover Problem [PDF]

open access: yes, 2016
We initiate the study of the classical Submodular Cover (SC) problem in the data streaming model which we refer to as the Streaming Submodular Cover (SSC).
Bazzi, Abbas   +5 more
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Communism – postcommunism continuum. The urban Romania in the 21st century

open access: yesSfera Politicii, 2013
While trying to understand the deeper meanings of the transition from communism to post communism in Romania, the study analyses the evolution of urban environment.
Tudor Pitulac
doaj  

Beyond Hyper-capitalism: can the sharing economy reshape sustainable development? [PDF]

open access: yes, 2017
In nowadays globalized world, highly interconnected by various kind of networks, first of all the social networks, a radical phenomenon is rapidly gaining momentum: that of the sharing economy. From the United States to the Eastern Europe, the phenomenon
Gurashi, Romina
core  

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Understanding Productivity Levels, Dispersion and Growth in the Leather Shoe Industry: Effects of Size and Informality [PDF]

open access: yes
In this case study performed on the industrial sub-sector of manufacture of leather shoes in Bolivia, we use the Hsieh and Klenow model (2008) to determine the differences between productivity of larger and formal companies and productivity of smaller ...
Carlos Gustavo Machicado   +1 more
core  

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