Results 71 to 80 of about 1,639 (298)
Higher education research in Asia: An archipelago, two continents or merely atomization?
, 2014 This study analyzes higher education research in Asia since the 1980s, based on internationally indexed publication data, focusing on research approaches and themes.
Horta, Hugo, Jung, Jisun
core +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
RUDN Journal of Political ScienceThe relevance of the topic presented in the article is determined primarily by the current foreign policy situation, namely the hybrid war unleashed by the collective West against the Russian Federation, a significant component of which are the so-called
Alexander V. Kurochkin
doaj +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
Molecular Oncology, EarlyView.This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source
SOME OF THE CAUSES OF THE »ATOMIZATION« OF THE RURAL FAMILY
, 1968 The term »atomization of the family« is taken by the author to mean the division of large »gentile« families (known in Yugoslavia as »family co-operatives«) into several conjugal families (including two generations only) and a further reduction of ...
Vojislav Đurić, Đurić, Vojislav
core
Communism – postcommunism continuum. The urban Romania in the 21st century
Sfera Politicii, 2013 While trying to understand the deeper meanings of the transition from communism to post communism in Romania, the study analyses the evolution of urban environment.
Tudor Pitulac
doaj
SOCIAL ATOMIZATION DURING THE PANDEMIC: CHANGING SOCIAL AND LABOR PRACTICES
Social & labor researches, 2021 The object of this research is the space of people's presence in Russia, the changes in its scale, and the social and labor practices implemented during the COVID-19 pandemic. The aim of the study is to assess the impact of the pandemic on the compression of the space of people's presence in the country, on the one hand, and to identify the prospects ...
openaire +1 more source
Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
FEBS Open Bio, EarlyView.Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source