Results 31 to 40 of about 1,639 (298)
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
AMBIGUOUS JANUS OF MODERN DEMOCRACY
Antropologìčnì Vimìri Fìlosofsʹkih Doslìdžen', 2016 Purpose. The purpose of the research is to analyze ambiguous concept of democracy as a phenomenon of political and social formation based on political and instrumental approach.
Volodymyr V. Khmil
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Homo tolerant in the value system “essentialism - existentialism”
RUDN journal of Sociology, 2023 The article is based on the data of the comparative sociological study of the latest wave of the EVS and WVS (2017-2022) and considers values through the opposition “essentialism - existentialism”.
A. A. Belov, A. N. Danilov, D. G. Rotman
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Orthodox Dissidence as De-atomization: Father Dmitrii Dudko and his Battle with Razobshchennost
, 2013 On June 20, 1980, after more than five months of imprisonment, grueling interrogation, and emotional anguish, Fr. Dmitrii Dudko appeared on Soviet television and disavowed his earlier “anti-Soviet” statements.
Ganson, Nicholas, Nicholas Ganson
core +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Atomization of society, new discriminations and trust under pandemic situation [PDF]
, 2021 Статтю присвячено аналізу особливостей процесу виробництва нових форм дискримінації в період пандемії та його наслідків для порядку соціальності. Показано, що пандемія знаходить вияв у докорінній трансформації повсякденності та в неможливості застосувати
Кочубейник, Ольга Миколаївна
core +1 more source
Amnis, 2003 If one looks today, with the historian's eyes, the South Cone at the end of the sixties and seventies and then, by continuation, turns a page of some years to fix the same part of the world, the report is very clear: the Latino-American subcontinent ...
Franck Gaudichaud
doaj +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source