Results 41 to 50 of about 11,733,884 (255)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Cambio, 2019 The article analyzes the relationship between social change and political change. The basic thesis is that, behind the widespread diagnosis of a political crisis a silencing "re-elaboration of the political" is happening.
Luca Raffini, Andrea Pirni
doaj +1 more source
Direct numerical simulation of an atomizing biodiesel jet: Impact of fuel properties on atomization characteristics [PDF]
, 2017 [EN] The utilization of biodiesel is an effective approach to reduce pollution from internal combustion engines and thus has attracted steadily increasing interest in the recent years.
Zaleski, Stéphane +7 more
core +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
AMBIGUOUS JANUS OF MODERN DEMOCRACY
Antropologìčnì Vimìri Fìlosofsʹkih Doslìdžen', 2016 Purpose. The purpose of the research is to analyze ambiguous concept of democracy as a phenomenon of political and social formation based on political and instrumental approach.
Volodymyr V. Khmil
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
, 2022 S.825-841When it comes to quality and efficiency, droplet diameters have a substantial impact on paint application processes. To determine droplet diameter distributions, Malvern-type laser diffraction and phase Doppler anemometry are common techniques ...
Weich, Daniel +3 more
core +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Atomization simulation and preparation of GH3536 powders at different atomization pressures [PDF]
, 2023 Spherical GH3536 alloy powders were prepared by vacuum induction-melting gas atomization method at the different atomization pressures (7, 8, 9 MPa). The region below the nozzle was numerically simulated by multiphase flow model and discrete phase model,
LIANG Jingjing +4 more
core +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source