Results 171 to 180 of about 16,388,948 (373)
Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho+11 more
wiley +1 more source
SOCIAL ORGANIZATION AND BEHAVIOR: A READER IN GENERAL SOCIOLOGY. Edited by Richard L. Simpson and Ida Harper Simpson. New York: John Wiley & Sons, 1964. 457 pp. $5.25 [PDF]
Warren Breed
openalex +1 more source
A discrete choice model with social interactions: an analysis of high school teen behavior [PDF]
We develop an empirical discrete choice model that explicitly allows for endogenous social interactions. We analyze the issues of multiple equilibria, statistical coherency, and estimation of the model by means of simulation methods.
Kooreman, Peter, Soetevent, Adriaan
core +1 more source
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp+13 more
wiley +1 more source
A study of the social behavior of a captive herd of giant tortoises
Llewellyn Thomas Evans, John V. Quaranta
openalex +1 more source
C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald+18 more
wiley +1 more source
Social Psychology: The Bases of the Behavior Called Social.
Margaret Floy Washburn, Robert H. Gault
openalex +2 more sources
Social value orientation as a moral intuition: Decision making in the dictator game. [PDF]
We studied the hypothesis that social value orientations are expressed automatically in behavior, as would be suggested by the social intuitionist model.
Cornelissen, Gert+2 more
core
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley +1 more source