Results 81 to 90 of about 838,994 (295)

Determinants of Board Members’ Intentions of Compliance and Ethical Behavior Regarding the Handling of Inside Information: Evidence from a Survey and Field Experiment [PDF]

open access: yesBusiness Ethics and Leadership
To effectively stimulate compliance, supervisory bodies need to understand which processes lead to non-compliance. The final responsibility for companies’ compliance lies with their board members. In this study, we applied Protection Motivation Theory to
Jeanette R. van der Lee   +3 more
doaj   +1 more source

ERBIN limits epithelial cell plasticity via suppression of TGF‐β signaling

open access: yesFEBS Letters, EarlyView.
In breast and lung cancer patients, low ERBIN expression correlates with poor clinical outcomes. Here, we show that ERBIN inhibits TGF‐β‐induced epithelial‐to‐mesenchymal transition in NMuMG breast and A549 lung adenocarcinoma cell lines. ERBIN suppresses TGF‐β/SMAD signaling and reduces TGF‐β‐induced ERK phosphorylation.
Chao Li   +3 more
wiley   +1 more source

Bases científicas y bioéticas del análisis de validez en medicina evaluadora

open access: yesMedicina y Seguridad del Trabajo, 2014
El contexto médico legal en el que se desarrolla la Medicina Evaluadora, permitiendo el acceso a prestaciones económicas, obliga a considerar la validez -firmeza, consistencia y valor legal- en las consultas de valoración médica de incapacidad.
Antonio Domínguez Muñoz   +5 more
doaj  

Redox‐dependent binding and conformational equilibria govern the fluorescence decay of NAD(P)H in living cells

open access: yesFEBS Letters, EarlyView.
In this work, we reveal how different enzyme binding configurations influence the fluorescence decay of NAD(P)H in live cells using time‐resolved anisotropy imaging and fluorescence lifetime imaging microscopy (FLIM). Mathematical modelling shows that the redox states of the NAD and NADP pools govern these configurations, shaping their fluorescence ...
Thomas S. Blacker   +8 more
wiley   +1 more source

Protocol for a randomized controlled trial of an internet-based prevention intervention for young children at-risk for functional abdominal pain

open access: yesTrials
Background Chronic pain often clusters in families, where parents and their offspring both experience chronic pain conditions. Young children of parents with irritable bowel syndrome (IBS) represent an at-risk group for the development of abdominal pain,
Rona L. Levy   +8 more
doaj   +1 more source

Social Behavior of the Black-Crowned Night Heron [PDF]

open access: bronze, 1938
Gladwyn Kingsley Noble   +2 more
openalex   +1 more source

Neutrophil deficiency increases T cell numbers at the site of tissue injury in mice

open access: yesFEBS Letters, EarlyView.
In wild‐type mice, injury or acute inflammation induces neutrophil influx followed by macrophage accumulation. Mcl1ΔMyelo (neutrophil‐deficient) mice lack neutrophils, and in response to muscle injury show fewer macrophages and exhibit strikingly elevated T‐cell numbers, primarily non‐conventional “double‐negative” (DN) αβ and γδ T cells.
Hajnalka Halász   +6 more
wiley   +1 more source

Anaemia prevalence and its associated factors in children under 5 years in Western China: a systematic review

open access: yesBMJ Paediatrics Open, 2022
Hein Raat   +7 more
doaj   +1 more source

Functional role and folding properties of the glucan‐binding domain of oral bacterial glucansucrase

open access: yesFEBS Letters, EarlyView.
The role of the glucan‐binding domain in Streptococcus sobrinus glucansucrase was examined, focusing on its impact on enzymatic activity, dextran binding, and structural stability of deletion mutants and a circularly permuted protein. Our research revealed that glucosyl transfer efficiency is linked to cooperative interdomain folding.
Hideyuki Komatsu   +5 more
wiley   +1 more source

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