Results 41 to 50 of about 290,839 (347)

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Economic Change and Cultural Evolution: The Ultimate Influence of Human Cognitive Limitations

open access: yesSocial Sciences
How cognitive limitations of individuals may affect the dynamics of cultural evolution under the effects of economic and technological forces is explored here.
Daniel Bordonaba-Bosque   +3 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Maternal Bonding in Early Infancy Predicts Childrens' Social Competences in Preschool Age

open access: yesFrontiers in Psychiatry, 2021
Background: There are many studies on mother-child-bonding with little theoretical doubt that better bonding may have a positive effect on further social development. However, there is hardly any empirical evidence.
Jens Joas, Eva Möhler
doaj   +1 more source

Globalization and social networks [PDF]

open access: yes, 2012
Globalization is a universal phenomenon that not only makes domestic economies restructure, but also may impact other areas of local societies. This paper studies the effect of globalization on human relations, in particular on the formation of social ...
Fischer, Justina A.V.
core  

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

How music-induced emotions affect sexual attraction: evolutionary implications

open access: yesFrontiers in Psychology
More than a century ago, Darwin proposed a putative role for music in sexual attraction (i.e., sex appeal), a hypothesis that has recently gained traction in the field of music psychology.
Manuela M. Marin   +3 more
doaj   +1 more source

Where's the harm? A social marketing approach to reframing 'problem' drinking cultures [PDF]

open access: yes, 2009
Alcohol consumption is often linked to a broad range of social and health problems, yet alcohol also plays a fundamental role in social bonding between people.
Carrigan, M.   +5 more
core  

Group involvement and self-rated health among the Japanese elderly: an examination of bonding and bridging social capital [PDF]

open access: yes, 2013
Background: To date, only a small amount of research on bonding/bridging social capital has separately examined their effects on health though they have been thought to have differential effects on health outcomes.
Doi, Hiroyuki   +4 more
core   +1 more source

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