Results 51 to 60 of about 290,839 (347)
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Gossiping for a Reason – Revised Gossip Functions Questionnaire (RGFQ)
Psychological Test Adaptation and Development: Introduction: According to one prominent theoretical model of gossip, we gossip for four key reasons: to keep track of our social networks, to strengthen bonds with others, to manage our reputation, and to entertain ourselves (Foster, 2004).
Meltem Yucel, Robert G. Moulder
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Movement Synchrony Forges Social Bonds Across Group Divides
Frontiers in Psychology, 2016 Group dynamics play an important role in the social interactions of both children and adults. A large amount of research has shown that merely being allocated to arbitrarily defined groups can evoke disproportionately positive attitudes toward one’s in ...
Bahar eTuncgenc +2 more
doaj +1 more source
Youth Culture and Islam in Indonesia [PDF]
, 2014 Indonesian youth culture is sometimes depicted through a moral panic discourse about mixed sex socializing. In this article, the authors challenge that view by presenting some ethnographic material on young Muslim Indonesians of both sexes socialising in
Mansfield, M. (Michelle) +1 more
core
Civil society in the South Caucasus: kinship networks as obstacles to civil participation [PDF]
, 2014 The research to date on informal networks of the post-communist South Caucasus has tended to focus either on the informal institutions’ role in providing social safety nets for the population or on the networks’ economic functions.
Aliyev, Huseyn
core +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Impact of group dancing during Japanese festivals on people’s sense of community
Frontiers in PsychologyMoving together or attending festivals has been reported to foster social bonding. However, whether festivals with and without dancing affect individuals’ social bonds and sense of community remains unclear.
Satoshi Kawase, Kei Eguchi
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
'I realised that I wasn't alone' : the views and experiences of young carers from a social capital perspective [PDF]
, 2011 The concept of social capital is very much an 'adult' concept, created by adults for adults, with children as the passive recipients of, primarily, parental social capital.
Barry, Monica
core +1 more source