Results 61 to 70 of about 21,702,173 (276)
Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
In this response to Lisa Trentin’s article, I explore themes that bring together research and activism, through engagement with the past, and the ethics that concerns such endeavours.
Zena Kamash
doaj +1 more source
Religious Rituals Increase Social Bonding and Pain Threshold
A key function of religious rituals is their ability to connect or bond individuals. Recent advances on the neurobiological underpinnings of bonding, highlighting how opioids are activated in the brain by social activities, can now be applied to the ...
S. Charles +9 more
semanticscholar +1 more source
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Economic Change and Cultural Evolution: The Ultimate Influence of Human Cognitive Limitations
How cognitive limitations of individuals may affect the dynamics of cultural evolution under the effects of economic and technological forces is explored here.
Daniel Bordonaba-Bosque +3 more
doaj +1 more source
Music and Language in Social Interaction: Synchrony, Antiphony, and Functional Origins
Music and language are universal human abilities with many apparent similarities relating to their acoustics, structure, and frequent use in social situations.
Nathan Oesch, Nathan Oesch
doaj +1 more source
The origins and function of musical performance
Music is widely recognised as a human universal, yet there is no agreed explanation for its function, or why and when it evolved. I summarise experimental evidence that the primary function of musicking lies in social bonding, both at the dyadic and ...
Robin I. M. Dunbar
doaj +1 more source
Personality homophily affects male social bonding in wild Assamese macaques (Macaca assamensis)
Animal social bonds are defined as stable, equitable and strong affiliative and cooperative relationships similar to human friendships. Just as human friendships, social bonds are thought to function as alliances that generate adaptive benefits via ...
Anja Ebenau +4 more
semanticscholar +1 more source
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Assisted living is a fast-growing living option for seniors who require residence-based activities for maintaining mental and physical health. Guided equine interactions may benefit seniors, so an on-site equine program was started at Hacienda at the ...
Ann Linda Baldwin +2 more
doaj +1 more source

