Results 61 to 70 of about 290,839 (347)

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Online experience sharing without explicit social interaction does not foster social bonding

open access: yesCyberpsychology: Journal of Psychosocial Research on Cyberpspace
Humans have a unique capacity to bond with others through shared experiences, even in the absence of explicit communication. Yet it is unknown whether this capacity is flexible enough to accommodate the different kinds of virtual environments on which ...
Wouter Wolf, Kayley Dotson
doaj   +1 more source

Is social capital associated with health ? Evidence from a study on the elderly italians [PDF]

open access: yes, 2016
In the last decades there had been undoubted improvements in medicine and living conditions, still the distribution of health within and between regions is facing an increasing unbalance and many researchers from different fields have tried to understand
AREZZO, Maria Felice
core  

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Bridge over troubled water?:Migration, social capital and the welfare state [PDF]

open access: yes, 2008
The problem of integrating non-Western immigrants into Western welfare states is the focus of this paper. To address this issue, we suggest a social capital approach in which we apply the conceptual pair of bridging social capital (BR), which connects an
Nannestad, Peter   +2 more
core   +2 more sources

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Social Brain Perspectives on the Social and Evolutionary Neuroscience of Human Language

open access: yesBrain Sciences
Human language and social cognition are two key disciplines that have traditionally been studied as separate domains. Nonetheless, an emerging view suggests an alternative perspective.
Nathan Oesch
doaj   +1 more source

Typology and Reasons for Murder Using Grounded Theory [PDF]

open access: yesمسائل اجتماعی ایران, 2018
Present study aims at typology and motives of murder convicts in Rasht Lakan prison. By means of qualitative method, this research conducted 10 individual and 3 as a group in-depth semi-structured interviews.
Ali Yaghoobi Choobari
doaj  

The Role of Mesotocin on Social Bonding in Pinyon Jays [PDF]

open access: yes, 2020
The neuropeptide oxytocin influences mammalian social bonding by facilitating the building and maintenance of parental, sexual, and same‐sex social relationships.
Allaire J.   +14 more
core   +2 more sources

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

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