Results 61 to 70 of about 11,986,581 (298)
Drugs, addiction, and the social bond [PDF]
Geography Compass, 2017 Abstract This article contributes towards the project of critically theorizing drug addiction by drawing on insights from psychoanalysis, anthropology, and geography. I argue that social bonds—that is, people's relationships to other people and to society—are central to the phenomenon of drug addiction, and I present three accounts of
openaire +2 more sources
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
Physical Education of StudentsBackground and Study Aim. Esports has emerged as a widespread leisure behavior among university students, yet its psychological consequences remain incompletely understood.
Şinasi Özsaydı, Özlem Sinem Uslu
doaj +1 more source
PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
Movement Synchrony Forges Social Bonds Across Group Divides
Frontiers in Psychology, 2016 Group dynamics play an important role in the social interactions of both children and adults. A large amount of research has shown that merely being allocated to arbitrarily defined groups can evoke disproportionately positive attitudes toward one’s in ...
Bahar eTuncgenc +2 more
doaj +1 more source
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
FEBS Open Bio, EarlyView.The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong +3 more
wiley +1 more source
Social Bonding, Early School Leaving, and Delinquency [PDF]
In this paper we investigate how successful social bonding theory is at predicting juvenile delinquency and school dropout behaviour. We adopt a simple dynamic approach which assumes that past involvement in risky behaviour reduces individual restraints ...
Traag Tanja +2 more
core
Understanding Juvenile Delinquent Behavior through Social Bonding
, 2019 Social control theory is often used to understand the many facets of social bonding opportunities and juvenile delinquency behavior. Various theories have been used to help explain delinquent behaviors and the reason for such actions against the ...
Gentle-Genitty, Carolyn
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FEBS Open Bio, EarlyView.The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley +1 more source