Results 81 to 90 of about 290,839 (347)

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Hierarchical social modularity in gorillas

, 2019
Modern human societies show hierarchical social modularity (HSM) in which lower-order social units like nuclear families are nested inside increasingly larger units.
Breuer, T., Groenenberg, M., Manguette, M., Morrison, R., Walsh, P.   +4 more
core   +1 more source

The walking library: mobilising books, places, readers and reading [PDF]

, 2017
The Walking Library, inaugurated in 2012, has functioned as a mobile laboratory and art project for the ongoing exploration of the relationships between environments, books, reading and writing.
Heddon, Deirdre, Myers, Misha
core   +1 more source

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

FEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi, Shunsuke Morioka, Keiko Morisawa, Kazutsugu Matsukawa, Shingo Ashida, Takeshi Suzuki, Shuji Sakamoto   +6 more
wiley   +1 more source

Rhythms of relief: perspectives on neurocognitive mechanisms of music interventions in ADHD

Frontiers in Psychology
Attention-deficit/hyperactivity disorder (ADHD) is a prevalent neurodevelopmental disorder characterized by multiple neurocognitive deficits. Research suggests that music interventions, both active and passive, may be an effective complementary method of
Zhihui Luo, Da-Wei Zhang
doaj   +1 more source

Social Bonding, Early School Leaving, and Delinquency [PDF]

In this paper we investigate how successful social bonding theory is at predicting juvenile delinquency and school dropout behaviour. We adopt a simple dynamic approach which assumes that past involvement in risky behaviour reduces individual restraints ...
Marie Olivier, Traag Tanja, Velden Rolf van der   +2 more
core   +1 more source

Two Types of Social Grooming Methods depending on the Trade-off between the Number and Strength of Social Relationships

, 2018
Humans use various social bonding methods known as social grooming, e.g. face to face communication, greetings, phone, and social networking sites (SNS). SNS have drastically decreased time and distance constraints of social grooming.
Takano, Masanori
core   +3 more sources

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Beyond perfect synchrony: shared interpersonal rhythmic timing enhances self-other merging judgements

Royal Society Open Science
Perfect synchrony is highly prosocial, yet interpersonal rhythms globally exhibit rich variation. In two online experiments, we tested the effect of varying interpersonal rhythms on self-other merging. First, we hypothesized that shared temporal features,
Dhwani P. Sadaphal, Christian R. Blum, Peter E. Keller, W. Tecumseh Fitch   +3 more
doaj   +1 more source

SCHOOL-BASED VIOLENCE AND PEACE: IMPROVING LEARNING IN HIGHER EDUCATION AMONG ADULT SURVIVORS OF SCHOOL BULLYING

International Studies Journal, 2023
Promoting equity and egalitarian society is very vital for enhancing human development, and one of the most powerful instruments for this purpose is education, which boosts people’s self-confidence, equips them for their future; to act responsibly in ...
Jonathan Chukwuemeka Madu, Abugu Solomon Ogbonna   +1 more
doaj