Results 51 to 60 of about 287,277 (297)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Gossiping for a Reason – Revised Gossip Functions Questionnaire (RGFQ)

open access: yesPsychological Test Adaptation and Development
: Introduction: According to one prominent theoretical model of gossip, we gossip for four key reasons: to keep track of our social networks, to strengthen bonds with others, to manage our reputation, and to entertain ourselves (Foster, 2004).
Meltem Yucel, Robert G. Moulder
doaj   +1 more source

Corporate marketing strategy using social media: a case study of the Ritz-Carlton Seoul [PDF]

open access: yes, 2017
With the increasing trend of popularity of websites and social networking sites, it is quite evident that companies need to take cautionary measures in protecting the reputations with respect to company and brands.
Kwag, Michael, Lee, Jung Wan
core   +2 more sources

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Movement Synchrony Forges Social Bonds Across Group Divides

open access: yesFrontiers in Psychology, 2016
Group dynamics play an important role in the social interactions of both children and adults. A large amount of research has shown that merely being allocated to arbitrarily defined groups can evoke disproportionately positive attitudes toward one’s in ...
Bahar eTuncgenc   +2 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Impact of group dancing during Japanese festivals on people’s sense of community

open access: yesFrontiers in Psychology
Moving together or attending festivals has been reported to foster social bonding. However, whether festivals with and without dancing affect individuals’ social bonds and sense of community remains unclear.
Satoshi Kawase, Kei Eguchi
doaj   +1 more source

'I realised that I wasn't alone' : the views and experiences of young carers from a social capital perspective [PDF]

open access: yes, 2011
The concept of social capital is very much an 'adult' concept, created by adults for adults, with children as the passive recipients of, primarily, parental social capital.
Barry, Monica
core   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

Communicating Toward Personhood [PDF]

open access: yes, 2009
Marshalling a mind-numbing array of data, Harvard political scientist Robert D. Putnam, in his book Bowling Alone, shows that on virtually every conceivable measure, civic participation, or what he refers to as “social capital,” is plummeting to levels ...
Gardner, Susan T.
core  

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