Results 151 to 160 of about 7,065,483 (350)

Changes in quality of care and costs induced by implementation of a diabetes program in a social security entity of Argentina

, 2013
Lorena González, Jorge F. Elgart, Calvo, José Gagliardino   +3 more
openalex   +2 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

A trans agent of social change in incarceration: A psychobiographical study of Natasha Keating. [PDF]

J Pers, 2023
du Plessis C, Halliwell SD, Mullens AB, Sanders T, Gildersleeve J, Phillips T, Brömdal A.   +6 more
europepmc   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Policy and Practice Implementation During Rapid Social Change: An Introduction to the Special Section. [PDF]

Glob Implement Res Appl, 2022
Ake G, Bertram R, Watrous J, Kerns SEU.
europepmc   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Health and Human Wellbeing in China: Do Environmental Issues and Social Change Matter? [PDF]

Front Psychol, 2022
Zhao W, Chang M, Yu L, Sohail MT.
europepmc   +1 more source

Job Stress And Attitude Change Of Teachers, Lawyers, Social Workers, And Nurses.

, 1979
Sally Wacker
openalex   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Social implementation trial of the ALD/NAFLD predictive model to increase health literacy and promote behaviour change

, 2023
Jun Motomura
openalex   +1 more source