Results 141 to 150 of about 7,119,137 (303)

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Psychobiographical trends: Untold stories and international voices in the context of social change. [PDF]

J Pers, 2023
Mayer CH.
europepmc   +1 more source

Introduction | Religion and Social Change in Ladakh [PDF]

, 2020
Beszterda, Rafał, Bray, John, Williams-Oerberg, Elizabeth   +2 more
core   +3 more sources

SOCIAL TOURISM- A FACTOR IN CULTURAL, SOCIAL AND ECONOMIC CHANGE [PDF]

Tourism has to maintain an individual and social balance, so that as well as providing personal fulfilment, it can be development in harmony with the human, natural and cultural environment and fit into a context of sustainable development.
Nicoleta-Rossela Dumitru
core  

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Challenges of social change: The 2021 Republic of Slovenia report card on physical activity of children and adolescents. [PDF]

J Exerc Sci Fit, 2023
Morrison SA, Jurak G, Starc G, Kovač M, Golobič M, Pavletič Samardžija P, Gabrijelčič M, Kotnik P, Meh K, Primožič M, Sember V.   +10 more
europepmc   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

A trans agent of social change in incarceration: A psychobiographical study of Natasha Keating. [PDF]

J Pers, 2023
du Plessis C, Halliwell SD, Mullens AB, Sanders T, Gildersleeve J, Phillips T, Brömdal A.   +6 more
europepmc   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Policy and Practice Implementation During Rapid Social Change: An Introduction to the Special Section. [PDF]

Glob Implement Res Appl, 2022
Ake G, Bertram R, Watrous J, Kerns SEU.
europepmc   +1 more source