Results 121 to 130 of about 40,371,065 (348)
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Why Public Access to Information and Communication Technologies (ICTs) Matter
, 2014 This research summary provides an overview of the Global Impact Study of Public Access to Information and Communication Technologies (ICTs). Libraries, telecenters, and cybercafés play a critical role in extending the benefits of information and ...
Group, Technology & Social Change
core
Intersubjectivity of Affect and Social Change
The main goal of the panel is to discuss a theoretical insight into the processes through which political affects could become intersubjective and create a potential for social change, particularly in the context of major societal crises such as the 2008
Nikolić, Olga +4 more
core +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Social Coordination and Social Change.
, 1996 Social and economic institutions govern how people interact with each other--they define the "rules of the game". Choosing the rules is at bottom a pure coordination problem, since people must agree on the rules in order to play. We posit that these rules evolve endogenously through the repeated interactions of individuals.
openaire +2 more sources
Journal of Integrative Environmental Sciences, 2019 The paper covers the public debate on BECCS (bioenergy with carbon capture and storage) between 2008 and 2018. Through a qualitative analysis of around 800 feature articles, editorials, and opinion pieces published in English, German, Swedish, Danish ...
Simon Haikola +2 more
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
User Survey Data Summaries [PDF]
, 2012 This document includes tables with counts and proportions of the majority of user survey questions. Open-ended questions, monetary answers, and numeric responses are not summarized.
Technology & Social Change Group
core
, 2017 How is social media different to traditional media in coverage of disruptive technological change? We explore how two entrants transforming the personal transportation and accommodation sectors are covered in social and traditional media.
Laurell, Christofer +6 more
core +1 more source