Results 131 to 140 of about 7,119,137 (303)
AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
Minority Influence: An Agenda for Study of Social Change. [PDF]
Front Psychol, 2022 Prislin R.
europepmc +1 more source
Social Change and Criminality in Istanbul [PDF]
Many researchers and urban planners have made studies about security in city centers. One of the prerequisites for the continuous development of cities is to establish a safe environment.
Cengiz Giritlioglu +2 more
core
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
BMJ Global HealthClimate change is a public health emergency. Yet, incongruously, the healthcare sector is a significant source of global greenhouse gas emissions.
Kee B Park +12 more
doaj +1 more source
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Variation in Implementing Dementia-Friendly Community Initiatives: Advancing Theory for Social Change. [PDF]
Geriatrics (Basel), 2023 Scher CJ, Greenfield EA.
europepmc +1 more source
Understanding Social and Behaviour Change Communication [PDF]
, 2015 terms that should be understood first, as different words and second as an entity. SBCC is primarily a brand of communication that has long existed in the social and behavioural disciplines; in the social sciences and humanities.
Iyorza, Stanislaus
core
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Social Media, Venue and the Right to a Fair Trial [PDF]
, 2019 Judicial failure to recognize social media\u27s influence on juror decision making has identifiable constitutional implications. The Sixth Amendment right to a fair trial demands that courts grant a defendant\u27s change of venue motion when media ...
Tenzer, Leslie Y. Garfield
core +1 more source