Results 61 to 70 of about 20,716,741 (337)

Organizations Driving Positive Social Change

, 2016
Academic and practitioner interest in how market-based organizations can drive positive social change (PSC) is steadily growing. This paper helps to recast how organizations relate to society.
U. Stephan, M. Patterson, Ciara M. Kelly, J. Mair   +3 more
semanticscholar   +1 more source

Using social and behavioural science to support COVID-19 pandemic response

Nature Human Behaviour, 2020
The COVID-19 pandemic represents a massive global health crisis. Because the crisis requires large-scale behaviour change and places significant psychological burdens on individuals, insights from the social and behavioural sciences can be used to help ...
J. V. Bavel, Katherine Baicker, Paulo S Boggio, V. Capraro, A. Cichocka, A. Cichocka, M. Cikara, M. Crockett, A. Crum, K. M. Douglas, James N. Druckman, J. Drury, Oeindrila Dube, N. Ellemers, E. Finkel, J. Fowler, M. Gelfand, Shihui Han, S. Haslam, J. Jetten, S. Kitayama, D. Mobbs, L. Napper, D. Packer, Gordon Pennycook, Ellen Peters, R. Petty, David G. Rand, S. Reicher, S. Schnall, A. Shariff, L. Skitka, S. Smith, C. Sunstein, Nassim Tabri, Joshua A. Tucker, S. Linden, P. Lange, Kim A. Weeden, Michael J. A. Wohl, Jamil Zaki, S. Zion, Robb Willer   +42 more
semanticscholar   +1 more source

The thioredoxin‐like and one glutaredoxin domain are required to rescue the iron‐starvation phenotype of HeLa GLRX3 knock out cells

FEBS Letters, EarlyView.
Glutaredoxin (Grx) 3 proteins contain a thioredoxin domain and one to three class II Grx domains. These proteins play a crucial role in iron homeostasis in eukaryotic cells. In human Grx3, at least one of the two Grx domains, together with the thioredoxin domain, is essential for its function in iron metabolism.
Laura Magdalena Jordt, Manuela Gellert, Finja Zelms, Sander Bekeschus, Christopher Horst Lillig   +4 more
wiley   +1 more source

Teachers as Agents of Social Change

Education for Social Change, 2016
Teachers are seen as key actors of change within programmes and projects on global learning. But all too often they are regarded in an instrumental way or as promoters of some form of ideal global teacher. Evidence from the UK and elsewhere suggests that
D. Bourn
semanticscholar   +1 more source

Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation

FEBS Letters, EarlyView.
The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt, Marcus S. Münchhoff, Jacqueline Krohn, Philip M. Palarz, Manuel H. Taft, Johannes N. Greve, Nataliya Di Donato, Falk F. R. Buettner, Dietmar J. Manstein   +8 more
wiley   +1 more source

Purification tags markedly affect self‐aggregation of CPEB3

FEBS Letters, EarlyView.
Although recombinant proteins are used to study protein aggregation in vitro, uncleaved tags can interfere with accurate interpretation. Our findings demonstrate that His₆‐GFP and His₁₂ tags significantly affect liquid droplet and amyloid fibril formation in the intrinsically disordered region (IDR) of mouse cytoplasmic polyadenylation element‐binding ...
Harunobu Saito, Yujin Lee, Motoharu Ueno, Naotaka Sekiyama, Masatomo So, Ayako Furukawa, Kenji Sugase   +6 more
wiley   +1 more source

Research capacity, motivators and barriers to conducting research among healthcare providers in Tanzania’s public health system: a mixed methods study

Human Resources for Health, 2023
Background Building health research capacity in low- and middle-income countries is essential to achieving universal access to safe, high-quality healthcare.
James T. Kengia, Albino Kalolo, David Barash, Cindy Chwa, Tuna Cem Hayirli, Ntuli A. Kapologwe, Ally Kinyaga, John G. Meara, Steven J. Staffa, Noor Zanial, Shehnaz Alidina   +10 more
doaj   +1 more source

Feeling Hopeful Inspires Support for Social Change

, 2016
Hope is an emotion that has been implicated in social change efforts, yet little research has examined whether feeling hopeful actually motivates support for social change.
Katharine H. Greenaway, A. Cichocka, R. V. Veelen, Tiina Likki, N. Branscombe   +4 more
semanticscholar   +1 more source

Insights into pegRNA design from editing of the cardiomyopathy‐associated phospholamban R14del mutation

FEBS Letters, EarlyView.
This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao, Qiangbing Yang, Christian J.B. Snijders Blok, Mark A. Daniels, Pieter A. Doevendans, Raymond Schiffelers, Joost P.G. Sluijter, Zhiyong Lei   +7 more
wiley   +1 more source

Reporting of surgical response to disasters in low-income and middle-income countries: a literature review

The Lancet Global Health, 2019
Background: Natural and man-made disasters can overwhelm the capacity of surgical systems in low-income and middle-income countries (LMICs). Most studies addressing peri-disaster surgical care focus on international relief efforts rather than on how ...
Luke Caddell, MS, Taylor Wurdeman, BS, Rolvix H Patterson, BA, Jordan Pyda, MD, Rachel Koch, MD, John G Meara, MD, Scott Corlew, MD   +6 more
doaj