Results 81 to 90 of about 7,095,562 (302)
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Advancing the domestic industrial production towards a sustainable, resource-preserving direction can become an important pillar to support competitiveness in the European Union, as well as in Hungary.
Mária Böröcz +3 more
doaj +1 more source
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Effect of Edtech Start-ups on Students’ Performance: Selected Evidence from Indian Cities
This paper attempts to examine how startups improve the performance of students and influence their affective elements towards studies. We chose the K-12 sector as it is the largest sector of edtech.
Amrin Fakih, Kala Seetharam Sridhar
doaj +1 more source
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Research on buddy programmes for newly arrived migrants focuses predominantly on integration outcomes. However, the intervention is also prone to reproducing power imbalances.
Gaëlle Mortier +2 more
doaj +1 more source
Growth and Diversification of Horticulture Crops in Karnataka
With the growth of technology, modernization, and changes in food habits, agricultural cropping pattern of the country has undergone a major shift in the recent past, moving away from the cereal to non-cereal crops cultivation, especially toward the ...
Komol Singha +2 more
doaj +1 more source
Big Data, Digitization, and Social Change (Ubiquity Symposium)
The term “big data” is something of a misnomer. Every generation of computers since the 1950s has been confronted with problems where data was way too large for the memory and processing power available.
Delic, Kemal A. +3 more
core +1 more source

