Results 41 to 50 of about 63,874 (260)

Cohesion or In-cohesion of Economic and Social Development of the UK's Regions

EUROPEAN RESEARCH STUDIES JOURNAL, 2022
PRACTICAL IMPLICATIONS: Regional development disparities may pose a threat to the territorial integrity of the United Kingdom. To avoid this scenario, it is crucial to continue efforts for regional economic and social cohesion.
Pastuszka, Sławomir, Pastuszka, Katarzyna   +1 more
openaire   +2 more sources

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Network cohesion and social support [PDF]

Social Networks, 2017
This article analyses the effects of personal network cohesion on different types of social support using two dimensions of cohesion: network closure (defined as a tightly knit set of actors around the ego) and cliquishness (defined as the extent to which an actor is connected with a number of cohesive sub-sets of alters).
Joel Martí, Mireia Bolíbar, Carlos Lozares   +2 more
openaire   +2 more sources

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Citizen participation and its impact on political efficacy: insights from a town hall study in Germany

Frontiers in Political Science
This study investigates political efficacy—citizens’ beliefs in their ability to understand politics (internal political efficacy) and influence outcomes (external political efficacy)—in the context of town hall meeting (THMs) participation in a German ...
Yann P. M. Rees, Yann P. M. Rees, Leon Walter, Jonas Rees, Jonas Rees   +4 more
doaj   +1 more source

Social cohesion matters in health [PDF]

International Journal for Equity in Health, 2013
The concept of social cohesion has invoked debate due to the vagueness of its definition and the limitations of current measurements. This paper attempts to examine the concept of social cohesion, develop measurements, and investigate the relationship between social cohesion and individual health.This study used a multilevel study design.
Chuang, Ying-Chih, Chuang, Kun-Yang, Yang, Tzu-Hsuan   +2 more
openaire   +2 more sources

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

تصور مقترح لمنهج الدراسات الاجتماعية بمرحلة التعليم الابتدائي في ضوء أبعاد التماسک الاجتماعي [PDF]

مجلة الجمعية التربوية للدراسات الاجتماعية, 2017
A proposed conceptualization of primary education social studies curriculum in light of social cohesion dimensions   The present study aimed at preparing a proposed conceptualization of primary education social studies curricula in light of social ...
إدريس سلطان صالح يونس
doaj   +1 more source