Results 71 to 80 of about 1,384,639 (301)

KOMPETENSI SOSIAL GURU DALAM PEMBELAJARAN DAN PENGEMBANGANNYA

open access: yesTa'dib, 2012
Social competence of teachers is very supportive in the teaching and learning processes, both in the classroom and outside the classroom. One of the competences is social competence.
Hasbi Ashsiddiqi
doaj   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

Health-Saving Competence of Future Primary School Teachers: Indicators of Development [PDF]

open access: yes, 2020
The research revealed an increasing interest of scientists to the problem of formation of health-saving competence of future primary school teachers. This tendency is due to the need for a social inquiry to modernize the training of future educators ...
Бондаренко, Геннадій Леонідович   +5 more
core  

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel   +4 more
wiley   +1 more source

TO THE PROBLEM OF SOCIAL COMPETENCE RESEARCH AS CONDITIONS OF PARTNER INTERACTION PARTICIPANTS OF THE REFORM PROCESS

open access: yesВісник: Київський інститут бізнесу та технологій, 2019
The problem of social competence as a condition for partnership interaction among participants in the process of educational innovation is presented in the article.
S. L. KRAVCHUK
doaj   +1 more source

Australian adolescents\u27 motor competence and perceptions of physical activity outcomes [PDF]

open access: yes, 2009
Benefits that are generally associated with physical activity include enjoyment of the activity, expectation of positive benefits, intention to exercise, perceived fitness or health self-efficacy, intrinsic motivation, and positive physical self ...
Hands, Beth P   +3 more
core   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

open access: yesFEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková   +3 more
wiley   +1 more source

Social and Cultural Capital and Learners’ Cognitive Ability: Issues and Prospects for Educational Relevance, Access and Equity Towards Digital Communication in Indonesia [PDF]

open access: yes, 2020
In the educational context, the necessity of recognizing the structure of relations among social and educational institutions by examining how individuals’ different social and cultural experiences affect the educational learning outcomes towards global ...
Maunah, Binti
core   +2 more sources

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