Results 111 to 120 of about 6,200,273 (303)
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Revista Facultad Nacional de Salud Pública, 2013 Objetivo: establecer la relación entre los determinantes sociales de la salud y la discapacidad en Santiago de Cali. Metodología: estudio descriptivo correlacional.
Consuelo Vélez A +2 more
doaj
Development under conditions of inequality and distrust: Social cohesion in Latin America [PDF]
"This paper analyzes the role of social cohesion in economic and institutional development and, broadly, the creation of welfare in Latin America. The paper defines the concept of social cohesion with reference to the notions of social capital and ...
Ferroni, Marco +2 more
core
What Shapes Health-Related Behaviors? The Role of Social Factors [PDF]
, 2011 Outlines how social factors such as education, income, and neighborhood conditions affect stress levels and access to healthy choices and medical care, in turn shaping health-related behaviors.
Colleen Barclay +2 more
core
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Psychopathological risks in children with migrant parents [PDF]
, 2009 In Western societies many immigrants live in difficult social and working conditions. Together with other factors, this state of affairs represents a risk for the well being of their children.
Bufacchi, Catia +1 more
core +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Lifestyles: from the individual to the context
Revista Facultad Nacional de Salud Pública, 2012 Lifestyles have been studied by different disciplines such associology, anthropology, and epidemiology. Both the termand the greatest developments in this regard stem from thesocial and cultural sciences, which consider lifestyles as groupbehavior ...
Luz S. Álvarez C.
doaj
Meteorological and social conditions contribute to infectious diarrhea in China. [PDF]
Sci Rep, 2021 Yang X, Xiong W, Huang T, He J.
europepmc +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source