Results 221 to 230 of about 21,610,538 (392)

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Screening for adverse social conditions in child healthcare settings: protocol for a systematic review. [PDF]

BMJ Open
Schwenker R, Alayli A, Rasch L, Ballmeyer C, Maguire JL, Cohen-Silver J, De Bock F.   +6 more
europepmc   +1 more source

Research Department - Population, Employment and Social Conditions - Building Industry - Correspondence with the Commonwealth Treasury - 1956 - 1965

, 2023

openalex   +1 more source

Social conditions for human happiness: A review of research.

International Journal of Psychology, 2015
R. Veenhoven
semanticscholar   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Mechanistic modeling of social conditions in disease-prediction simulations via copulas and probabilistic graphical models: HIV case study. [PDF]

Health Care Manag Sci
Khosheghbal A, Haas PJ, Gopalappa C.
europepmc   +1 more source

Higher prevalence of depressed mood in immigrants' offspring reflects their social conditions in the host country: The HELIUS study. [PDF]

PLoS One, 2020
Stronks K, Şekercan A, Snijder M, Lok A, Verhoeff AP, Kunst AE, Galenkamp H.   +6 more
europepmc   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Les prestations familiales et sociales sous conditions de ressource au risque de la crise [PDF]

, 2011
Franck von Lennep
openalex   +1 more source

Social conditions facilitate water conservation in a solitary bee. [PDF]

J Insect Sci
Ostwald MM, Venegas VA, Seltmann KC.
europepmc   +1 more source