Results 131 to 140 of about 3,216,649 (304)

The Social Construction of Spinsterhood Among the Pekal Tribe in Napal Putih, North Bengkulu Regency

Sinthop
This study explores the social construction of spinsterhood among the Pekal Tribe, who predominantly inhabit Napal Putih in North Bengkulu Regency. The research investigates the socio-cultural meanings attached to unmarried women of a certain age and ...
Ferdy Safutra, Lesti Heriyanti, Susiyanto Susiyanto   +2 more
doaj   +1 more source

The Social Construction of Narratives and Arguments in Animal Welfare Discourse and Debate. [PDF]

Animals (Basel), 2022
Muhammad M, Stokes JE, Morgans L, Manning L.   +3 more
europepmc   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Reporting and social construction of race in Alzheimer's disease clinical trials. [PDF]

Alzheimers Dement, 2022
Hu WT.
europepmc   +1 more source

Social Construction: Understanding Construction in a Human Context [PDF]

As lean construction has evolved as a practice, efforts have been made to develop theoretical foundations for understanding it. These efforts have been informed by our understanding of lean manufacturing, a source of many of the seminal ideas for lean ...
Howell, Gregory, Koskela, Lauri, Rooke, John, Slivon, Christine   +3 more
core  

Constructing the cultural repertoire in a natural disaster: The role of social media in the Thailand flood of 2011 [PDF]

, 2014
In 2011, Thailand witnessed its worst flooding catastrophe in half a century. In this study, we explored social media as a new and promising weapon to address the physical and morale challenges caused by the natural disaster.
Hackney, R, Kaewkitipong, L, Mao, M, Pan, SL, Ractham, P   +4 more
core   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Dynamics of the social construction of knowledge: an empirical study of Zhihu in China. [PDF]

EPJ Data Sci, 2022
Zhang L, Li YN, Peng TQ, Wu Y.
europepmc   +1 more source

'How to feel safe': international students study migration [PDF]

, 2012
A variety of institutional and representational mechanisms are used in the construction of 'international students' and other 'migrants' or 'ethnic minorities' as two distinctive social categories. As part of these construction processes, the individuals
Shachar, Itamar
core  

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source