Results 41 to 50 of about 133,886 (308)
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Deepfake as a social-technical artifact: A sociological analysis
RUDN journal of SociologyDeepfakes as digital artifacts created with deep machine learning have already become a common phenomenon with multiple forms, but social consequences of this technology are still controversial.
I. V. Katernyi +2 more
doaj +1 more source
Determinants of Emerging Technology Adoption For Safety Among Construction Businesses [PDF]
, 2022 This study aims to identify the antecedents of emerging technology adoption in construction businesses. The objectives of this study were to identify the determinants and barriers to the adoption of emerging technologies in the construction industry ...
Alzoubi, Haitham M. +4 more
core
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
THE RELATIONSHIP BETWEEN TECHNICAL AND SOCIAL NORMS IN ENVIRONMENTAL PROJECT
Rudarsko-geološko-naftni Zbornik, 1992 In the article the relationship between system of technical and system of social norms in ecological project has been considered from constructivist standpoint in sociology of technology.
Jasminka Lažnjak
doaj
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Social Embeddedness of Technology: Prospective Research Areas
Foresight and STI Governance, 2015 Strategic documents that reflect future S&T priorities are often formulated without sufficiently taking into account the social context of S&T developments.
Mariya Dobryakova, Zoya Kotel'nikova
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
The evolution and predicament of modern social technicalization
Cultures of Science, 2023 Social technicalization refers to the construction and operation of society in accordance with the principles of technology. The stage of modern social technicalization was spawned after the Industrial Revolution and has mainly been manifested in two ...
Jie Song
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