Results 51 to 60 of about 133,886 (308)
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Robots and AR: towards a platform economy for construction
, 2019 Platform economies like Uber and AirBnB have emerged quickly to dominate and radically reconfiguring social, geographic and organisational structures of existing economic systems; putting markets into a state of contingency and flux.
McMeel, D
core +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Planning and implementation of effective collaboration in construction projects [PDF]
, 2007 The 21st century is now seen as the time for the construction industry to embrace new ways of working if it is to continue to be competitive and meet the needs of its ever demanding clients.
Shelbourn, M +3 more
core +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Current Swedish Archaeology, 2006 In this paper the authors problematize the relation between technological and social aspects of archaeological fieldwork through a historical case study of the introduction and use of compressed air technology in archaeology.
Åsa Gillberg, Ola W. Jensen
doaj +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Data & PolicyEthical guidelines and policy documents destined to guide AI innovations have been heralded as the solution to guard us against harmful effects or to increase public value. However, these guidelines and policy documents face persistent challenges.
Frederic Heymans, Rob Heyman
doaj +1 more source
, 2023 Purpose: Although prefabricated construction (PC) technology has attracted considerable attention worldwide because of its significant role in the global fight against COVID-19, market-driven adoption is still limited.
Yuan, Mengqi +6 more
core +1 more source